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Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

This protocol demonstrates single-molecule surface-enhanced Raman scattering (SERS) measurements using a DNA origami nanoantenna (DONA) combined with colocalized atomic force microscopy (AFM) and Raman...

Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy

Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy

Described here is a nanosphere lithography method for parallel fabrication of zero mode waveguides, which are arrays of nanoapertures in a metal-clad glass microscopy coverslip for single molecule imaging at nano- to micromolar concentrations of fluorophores. The method takes advantage of colloidal crystal self-assembly to create a waveguide...

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

We describe the detailed protocol for the DNA origami-based assembly of gold nanorods into chiral plasmonic metamolecules with strong chiroptical responses. The protocol is not limited to chiral configurations and can be easily adapted for the fabrication of various plasmonic...

Colloidal Synthesis of Nanopatch Antennas for Applications in Plasmonics and Nanophotonics

Colloidal Synthesis of Nanopatch Antennas for Applications in Plasmonics and Nanophotonics

A protocol for the colloidal synthesis of silver nanocubes and fabrication of plasmonic nanoscale patch antennas with sub-10 nm gaps is...

Preparation of Mica and Silicon Substrates for DNA Origami Analysis and Experimentation

Preparation of Mica and Silicon Substrates for DNA Origami Analysis and Experimentation

Reproducible cleaning processes for substrates used in DNA origami research are described, including bench-top RCA cleaning and derivatization of silicon oxide. Protocols for surface preparation, DNA origami deposition, drying parameters, and simple experimental set-ups are...

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

The procedure for implementing a refractive index sensor for terahertz frequencies based on a grooved parallel-plate waveguide geometry is described here. The method yields a measurement of the refractive index of a small volume of liquid through monitoring of the shift in the resonant frequency of the waveguide...

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Updated: Jan 19, 2026

Author Spotlight: Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

Author Spotlight: Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

Published on: July 21, 2023

Una guía de ondas plasmónica de origami de baja pérdida

Fiorenzo Vetrone¹, Federico Rosei²

¹Institute of Fundamental and Frontier Science, University of Electronic Science and Technology of China, No. 4, Section 2, North Jianshe Road, Chengdu 610051, China, and Centre Énergie, Matériaux et Télécommunications, Institut National de Recherche Scientifique, Université du Québec, Varennes, Québec J3X 1S2, Canada.

Science (New York, N.Y.)

|August 5, 2017

Resumen

No abstract available in PubMed .

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Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy

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