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Updated: Feb 24, 2026

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Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence
Published on: October 25, 2011
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Microambientes inmunitarios tumorales heterogéneos entre las metástasis de crecimiento diferencial en una paciente
Alejandro Jiménez-Sánchez1, Danish Memon2, Stephane Pourpe3
1Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
Cell
|August 26, 2017
Resumen
En el cáncer de ovario, coexisten microambientes inmunes tumorales distintos, lo que explica las diversas respuestas de la lesión metastásica al tratamiento. La inmunogenómica revela la infiltración de células inmunes en los tumores en regresión frente a la exclusión en los que progresan.
Área de la Ciencia:
- En el campo de la oncología
- Inmunología
- La genómica
Sus antecedentes:
- El cáncer de ovario seroso de alto grado (HGSOC) a menudo se trata con múltiples regímenes de quimioterapia.
- Las lesiones metastásicas pueden exhibir respuestas heterogéneas a la terapia, con algunas que progresan mientras que otras retroceden.
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