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Updated: Jul 28, 2026
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Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
Published on: April 1, 2015
Las varices esofágicas asociadas con la terapia de combinación busulfano-tioguanina para la leucemia mieloide crónica
N S Key1, P M Kelly, P M Emerson
1Department of Haematology, John Radclife Hospital, Oxford.
Lancet (London, England)
|November 7, 1987
Resumen
El tratamiento continuo con busulfano y 6-tioguanina para la leucemia mieloide crónica (LMC) puede causar problemas hepáticos. Esta terapia combinada está relacionada con la hiperplasia regenerativa nodular (HNR), lo que lleva a la hipertensión portal y las varices esofágicas en los pacientes.
Área de la Ciencia:
- Hepatología Hepatología.
- Oncología Oncología.
- Farmacología Farmacología.
Sus antecedentes:
- La leucemia mieloide crónica (LMC) es una neoplasia mieloproliferativa.
- El busulfano y la 6-tioguanina son agentes de quimioterapia utilizados en el tratamiento de la LMC.
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