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Updated: Feb 17, 2026

Single-Molecule FRET Imaging for Observing the Conformational Dynamics of Dynamin-Like GTPase Atlastin
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La actividad del factor de necrosis tumoral α está modulada por reordenamientos conformativos dinámicos

Daniela Hofmann1, Loïc Salmon1, Gerhard Wider1

  • 1Institute of Molecular Biology and Biophysics, ETH Zürich , 8093 Zürich, Switzerland.

Journal of the American Chemical Society
|December 2, 2017
PubMed
Resumen

Se estudió la inactivación del factor de necrosis tumoral α (TNFα) mediante RMN. Perturbar la interfaz TNFα aumenta su dinámica, ofreciendo nuevas estrategias para atacar enfermedades inflamatorias.

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