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Autoensamblaje de Tetartoide Quiral Metálico y Orgánico
Dong Luo1, Xue-Zhi Wang2, Chen Yang3
1College of Chemistry and Materials Science, Jinan University , Guangzhou 510632, P. R. China.
Journal of the American Chemical Society
|December 14, 2017
Resumen
Los investigadores sintetizaron nuevas jaulas quirales de cobalto-imidazolato con una estructura tetartoide única. Estas jaulas pueden resolverse en cristales homoquirales o formarse a través de la inducción quiral, destacando el papel de los sustituyentes en la formación de la jaula.
Área de la Ciencia:
- Química de la coordinación
- Química supramolecular
- Ciencias de los materiales
Sus antecedentes:
- Las jaulas de coordinación quiral ofrecen entornos internos precisos para materiales moleculares avanzados.
- El autoensamblaje es una estrategia clave para construir estructuras supramoleculares complejas.
Objetivo del estudio:
- Para sintetizar nuevas jaulas quirales de cobalto-imidazolato de 20 núcleos con una estructura tetartoide.
- Investigar métodos para obtener jaulas homoquirales y comprender los efectos de dirección de la estructura.
Principales métodos:
- Autoensamblaje de 72 subcomponentes para formar jaulas de cobalto-imidazolato.
- Resolución espontánea de las mezclas racémicas en cristales conglomerados.
- Inducción quiral mediante el uso de enantiómeros de d- y l-mentol.
Principales resultados:
- Se sintetizó con éxito una serie de jaulas quirales de cobalto-imidazolato de 20 núcleos con una nueva estructura tetartoide.
- La resolución espontánea dio lugar a jaulas tetartoidales racémicas (Δ y Λ) como cristales conglomerados.
- Las jaulas homoquirales Δ y Λ se obtuvieron mediante inducción quiral con (d) - y (l) -mentol, respectivamente.
- Se encontró que el sustituto 2-metilo en el grupo imidazolilo era crítico para la formación de la jaula tetartoide; su ausencia condujo a una jaula cúbica.
Conclusiones:
- El estudio demuestra la síntesis exitosa de jaulas quirales tetartoidales de cobalto-imidazolato.
- La inducción quiral proporciona una ruta efectiva hacia las jaulas enantiopuras.
- Los efectos estéricos de los sustituyentes juegan un papel crucial en la dirección del resultado del autoensamblaje y la estructura final de la jaula.
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