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El entrenamiento inmunológico libera el potencial innato
Wilbur M Song1, Marco Colonna1
1Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA.
Cell
|January 13, 2018
Resumen
La inmunidad entrenada ofrece una memoria inmune innata distinta de la memoria adaptativa. Estudios recientes exploran sus mecanismos y consecuencias celulares y de todo el organismo.
Área de la Ciencia:
- Inmunología
- La inmunidad innata
- Memoria inmune
Sus antecedentes:
- La inmunidad entrenada representa una forma de memoria inmune innata.
- Posee características distintas en comparación con la memoria inmune adaptativa.
Objetivo del estudio:
- Para aclarar los mecanismos subyacentes a la inmunidad entrenada.
- Investigar las consecuencias funcionales de la inmunidad entrenada a nivel celular y orgánico.
Principales métodos:
- Análisis de cinco estudios del Consorcio Internacional de Inmunidad entrenada.
- Investigación a través de los niveles celulares y de todo el organismo.
Principales resultados:
- Los estudios proporcionan información sobre los mecanismos de la inmunidad entrenada.
- Se destacan las consecuencias funcionales tanto a nivel celular como a nivel de todo el organismo.
Conclusiones:
- La inmunidad entrenada es un área importante de la investigación inmune innata.
- Una mayor comprensión de la inmunidad entrenada tiene amplias implicaciones para la salud y la enfermedad.
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