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Bases estructurales de la iniciación de la transcripción por la ARN polimerasa III

Guillermo Abascal-Palacios1, Ewan Phillip Ramsay1, Fabienne Beuron1

  • 1The Institute of Cancer Research, London SW7 3RP, UK.

Nature
|January 19, 2018
PubMed
Resumen

Los investigadores visualizaron los complejos de iniciación de transcripción de la ARN polimerasa (Pol) III utilizando microscopía electrónica. La unión de TFIIIB reestructura Pol III, facilitando la apertura del ADN y la iniciación de la transcripción, revelando mecanismos conservados en las polimerasas.

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