Video Experimental Relacionado
Updated: Feb 14, 2026
12:32
The Effect of Anodization Parameters on the Aluminum Oxide Dielectric Layer of Thin-Film Transistors
Published on: May 24, 2020
9.3K
Electrolisis acoplada anodicamente para la heterodifuncionalización de alquenos
Ke-Yin Ye1, Gisselle Pombar1,2, Niankai Fu1
1Department of Chemistry and Chemical Biology, Cornell University , Ithaca, New York 14853, United States.
Journal of the American Chemical Society
|February 7, 2018
Resumen
Los nuevos métodos electroquímicos permiten reacciones orgánicas difíciles. La electrólisis acoplada anodicamente ofrece una estrategia complementaria para las transformaciones redox, específicamente para lograr la metilación selectiva de clorotrifluoroalquenos.
Área de la Ciencia:
- Química orgánica
- La electroquímica
- Catálisis
Sus antecedentes:
- Los métodos tradicionales de síntesis orgánica se enfrentan a limitaciones para las transformaciones redox complejas.
- La fotoquímica y la electroquímica ofrecen nuevas estrategias catalíticas para las reacciones orgánicas.
- Los métodos electroquímicos proporcionan vías únicas para las transformaciones oxidativas.
Objetivo del estudio:
- Explorar la electrólisis acoplada anodicamente como método complementario para las transformaciones redox orgánicas.
- Demostrar la utilidad de la electrólisis acoplada anodicamente para lograr reacciones orgánicas difíciles.
- Mostrar la cloro trifluorometilación regio y quimioselectiva de los alquenos utilizando este enfoque electroquímico.
Principales métodos:
- Utilizando la electrólisis acoplada anodicamente, un proceso electroquímico que implica dos eventos oxidativos paralelos.
- Aplicación de este método a la funcionalización de los alquenos.
- Centrarse en lograr una alta regionalidad y quimioselectividad en la reacción.
Principales resultados:
- Demostración exitosa de la electrólisis acoplada anodicamente para las transformaciones redox orgánicas.
- Se ha conseguido la metilación regio y quimioselectiva de clorotrifluoroalquenos.
- Estableció una nueva estrategia electroquímica para la funcionalización de alceno.
Conclusiones:
- La electrólisis acoplada anodicamente es una herramienta poderosa y versátil para la síntesis orgánica.
- Esta estrategia electroquímica proporciona una alternativa valiosa a los métodos existentes para las transformaciones redox.
- La demostración de la clorotrifluorometilación pone de relieve el potencial de esta técnica para la síntesis de moléculas complejas.
Más Videos Relacionados
Videos de Conceptos Relacionados
03:00Electrolysis
30.6K
In a galvanic cell, the electrical work is done by a redox system on its surroundings as electrons produced by the spontaneous redox reactions are transferred through an external circuit. Alternatively, an external circuit does work on a redox system by imposing a voltage sufficient to drive an otherwise nonspontaneous reaction in a process known as electrolysis. For instance, recharging a battery involves the use of an external power source to drive the spontaneous (discharge) cell reaction in...
30.6K
01:22Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction
2.4K
The radical dimerization of ketones or aldehydes gives vicinal diols through a pinacol coupling reaction. However, the behavior of titanium metals used for the reaction as a source of electrons is unusual. When the reaction is carried out in the presence of titanium, diols can be isolated at low temperatures. Else titanium further reacts with diols, forming alkenes through the McMurry reaction.
2.4K
02:29Nomenclature of Alkenes
16.2K
The IUPAC naming system for alkenes replaces -an- with -en- in the corresponding parent alkanes. Accordingly, a simple alkene replaces the -ane suffix of the alkane with -ene.
As per the IUPAC rules, the longest carbon chain containing the maximum number of double bonds is identified as the parent chain and is numbered such that the doubly bonded carbon atoms receive the lowest possible numbers. The location of the double bond is indicated by the number of its first carbon atom. In branched...
As per the IUPAC rules, the longest carbon chain containing the maximum number of double bonds is identified as the parent chain and is numbered such that the doubly bonded carbon atoms receive the lowest possible numbers. The location of the double bond is indicated by the number of its first carbon atom. In branched...
16.2K
02:01Isomerism in Alkenes
15.3K
Alkenes like 1-butene and 2-butene exhibit constitutional isomerism, as they differ in the position of the double bond. Further, 2-butene exhibits stereoisomerism and exists as two distinct compounds differing in spatial arrangement.
An isomer is called cis-2-butene when the methyl groups are on the same side of the double bond, and the other stereoisomer, in which methyl groups are on the opposite side of the double bond, is called trans-2-butene. The cis and trans stereoisomers are not...
An isomer is called cis-2-butene when the methyl groups are on the same side of the double bond, and the other stereoisomer, in which methyl groups are on the opposite side of the double bond, is called trans-2-butene. The cis and trans stereoisomers are not...
15.3K
02:46Halogenation of Alkenes
19.2K
Halogenation is the addition of chlorine or bromine across the double bond in an alkene to yield a vicinal dihalide. The reaction occurs in the presence of inert and non-nucleophilic solvents, such as methylene chloride, chloroform, or carbon tetrachloride.
Consider the bromination of cyclopentene. Molecular bromine is polarized in the proximity of the π electrons of cyclopentene. An electrophilic bromine atom adds across the double bond, forming a cyclic bromonium ion intermediate.
Consider the bromination of cyclopentene. Molecular bromine is polarized in the proximity of the π electrons of cyclopentene. An electrophilic bromine atom adds across the double bond, forming a cyclic bromonium ion intermediate.
19.2K
01:20Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)
1.7K
Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
1.7K