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Terapia con ejercicios y toxicidad cardiovascular en el cáncer
Jessica M Scott1, Tormod S Nilsen2, Dipti Gupta3
1Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY (J.M.S., D.G., L.W.H.). scottj1@mskcc.org.
Circulation
|March 14, 2018
Resumen
El ejercicio puede ayudar a preservar la salud cardiovascular en pacientes con cáncer que experimentan cardiotoxicidad por los tratamientos contra el cáncer. Esta revisión explora el ejercicio
Área de la Ciencia:
- Cardio-oncología
- Enfermedad cardiovascular
- Fisiología del ejercicio
Sus antecedentes:
- Los tratamientos contra el cáncer pueden causar disfunción cardíaca (cardiotoxicidad), afectando a todo el sistema cardiovascular.
- Esta toxicidad puede conducir a insuficiencia cardíaca y enfermedad arterial coronaria.
- Las estrategias para mejorar la reserva cardiovascular son cruciales.
Objetivo del estudio:
- Revisar la eficacia y tolerabilidad de las intervenciones de ejercicio para controlar la cardiotoxicidad en pacientes adultos con cáncer.
- Proponer un marco de investigación para las prescripciones de ejercicios personalizados.
Principales métodos:
- Revisión de la literatura sobre las intervenciones de ejercicio en pacientes con cáncer con cardiotoxicidad.
- Análisis de los datos existentes sobre los efectos del ejercicio sobre la reserva cardiovascular.
- Desarrollo de un marco conceptual para la evaluación personalizada de riesgos.
Principales resultados:
- El entrenamiento físico es un método reconocido para mejorar la reserva cardiovascular en poblaciones sin cáncer.
- La evidencia sugiere que el ejercicio puede mitigar la toxicidad cardiovascular en pacientes con cáncer.
- Se necesita más investigación para estrategias de ejercicio personalizadas.
Conclusiones:
- Las intervenciones de ejercicio son prometedoras para prevenir o controlar la toxicidad cardiovascular inducida por el tratamiento del cáncer.
- Las recetas de ejercicio personalizadas son la clave para optimizar los resultados.
- Se propone un marco de investigación para orientar los estudios futuros.
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