Video Experimental Relacionado

Updated: Feb 11, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
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Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

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Enfoque químico para la designación de un tratamiento personalizado en el cáncer de pulmón

Elizabeth A McMillan1, Myung-Jeom Ryu2, Caroline H Diep1

  • 1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Cell
|April 24, 2018
PubMed
Resumen

Los investigadores descubrieron nuevos objetivos farmacológicos para el cáncer de pulmón mediante la detección de una gran biblioteca química contra modelos de células cancerosas. Este enfoque identificó 171 vínculos químico-genéticos, revelando vulnerabilidades en tipos específicos de cáncer que carecen de tratamientos efectivos.

Palabras clave:
El mutante KRASSeñalización NRF2Identificación del objetivo del cáncerBiología químicaciliogénesisTratamientos con glucocorticoidesCáncer de pulmónBiosíntesis de las serinas

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