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Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
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La resonancia magnética cardiovascular en el infarto agudo del miocardio de elevación del segmento ST: avances
Heerajnarain Bulluck1,2, Rohan Dharmakumar3,4, Andrew E Arai5
1Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London, United Kingdom (H.B., D.J.H.).
Circulation
|May 2, 2018
Resumen
Los nuevos avances en imágenes de resonancia magnética cardiovascular ayudan a evaluar el tamaño del ataque cardíaco (infarto de miocardio) y orientar nuevas terapias. Esta tecnología ofrece información sobre el daño cardíaco y la remodelación después del infarto de miocardio por elevación ST, mejorando los resultados de los pacientes.
Área de la Ciencia:
- Cardiología
- Imágenes médicas
- Ingeniería biomédica
Sus antecedentes:
- La mortalidad por infarto de miocardio por elevación del segmento ST está disminuyendo, pero la incidencia de insuficiencia cardíaca después del infarto de miocardio está aumentando.
- Los tratamientos actuales carecen de estrategias efectivas para reducir el tamaño del infarto más allá de la intervención coronaria percutánea primaria.
- Las nuevas terapias cardioprotectoras son cruciales para mejorar los resultados en pacientes con infarto de miocardio con elevación ST.
Objetivo del estudio:
- Revisar los avances recientes en las imágenes de resonancia magnética cardiovascular (CMR) para el infarto de miocardio de elevación ST.
- Discutir el papel de la CMR en la evaluación de nuevas terapias cardioprotectoras.
- Explorar las futuras aplicaciones de la CMR en el manejo del IM de elevación ST.
Principales métodos:
- Utilizando el mapeo multiparametrico de imágenes de resonancia magnética cardiovascular.
- Evaluar el edema miocárdico, la obstrucción microvascular y la hemorragia intramiocárdica.
- Evaluar los cambios en el espacio intersticial miocárdico remoto.
Principales resultados:
- CMR permite una evaluación precisa del tamaño del MI y la remodelación ventricular izquierda adversa.
- El mapeo multiparamétrico proporciona información detallada sobre la fisiopatología de la lesión miocárdica.
- La CMR es fundamental para evaluar la eficacia de los tratamientos cardioprotectores emergentes.
Conclusiones:
- La resonancia magnética cardiovascular es una herramienta clave para evaluar nuevas terapias en el MI de elevación ST.
- Los avances en la RMC, en particular el mapeo multiparamétrico, mejoran la comprensión de los cambios cardíacos posteriores al infarto.
- Las aplicaciones futuras de CMR son significativamente prometedoras para mejorar la atención al paciente y los resultados después del infarto de miocardio por elevación de ST.
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