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Updated: Feb 10, 2026

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
08:55

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis

Published on: August 7, 2018

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Mejor juntos: un amiloide híbrido señala la necroptosis

Dan Li1, Cong Liu2

  • 1Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200230, China.

Cell
|May 19, 2018
PubMed
Resumen

Los investigadores descubrieron la estructura de alta resolución del complejo de señalización RIPK1-RIPK3, revelando cómo forma hetero-amiloides para mediar la muerte celular programada (necroptosis). Esta plataforma amiloide funcional recluta y activa socios de señalización posteriores.

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