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Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
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Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

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Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
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Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

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Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
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Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

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Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
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Parkinson Disease l: Introduction01:24

Parkinson Disease l: Introduction

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Parkinson’s disease is a chronic, progressive neurodegenerative disorder that primarily affects movement. It is characterized by motor symptoms such as resting tremors, muscle rigidity, bradykinesia (slowness of movement), and postural instability. Patients may notice hand tremors at rest, stiffness during movement, or a shuffling gait. In addition to motor features, non-motor symptoms include sleep disturbances, mood and behavioral changes, constipation, and cognitive impairment, all of...
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In vivo Imaging of Transgenic Leishmania Parasites in a Live Host
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In vivo Imaging of Transgenic Leishmania Parasites in a Live Host

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La leishmaniosis

Sakib Burza1, Simon L Croft2, Marleen Boelaert3

  • 1Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK; Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium; Médecins Sans Frontières, Delhi, India.

Lancet (London, England)
|August 22, 2018
PubMed
Resumen
Este resumen es generado por máquina.

La leishmaniasis, una enfermedad tropical descuidada, afecta a millones de personas en todo el mundo. Si bien se están logrando progresos en algunas regiones, el aumento de los conflictos y los desplazamientos mantienen los casos, lo que pone de relieve la necesidad urgente de nuevas herramientas y tratamientos de control.

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Área de la Ciencia:

  • Medicina tropical
  • Enfermedades infecciosas
  • Salud pública

Sus antecedentes:

  • La leishmaniasis es una enfermedad parasitaria relacionada con la pobreza con un impacto global significativo.
  • Se presenta como leishmaniasis visceral (VL) y leishmaniasis cutánea (CL), que afecta a 0,7-1 millones de personas al año.
  • La OMS clasifica la leishmaniosis como una enfermedad tropical descuidada prioritaria.

Objetivo del estudio:

  • Para resumir la situación actual de la leishmaniasis en todo el mundo.
  • Destacar los desafíos en el control de enfermedades y la necesidad de nuevas intervenciones.

Principales métodos:

  • Revisión de los datos y tendencias mundiales de casos de leishmaniasis.
  • Análisis de los factores que influyen en la transmisión y el control de enfermedades.

Principales resultados:

  • Los casos reportados de VL han disminuido en Asia debido a la mejora del diagnóstico, el tratamiento y el control de vectores.
  • El este de África continúa reportando casos sostenidos de VL.
  • El conflicto y el desplazamiento han causado un aumento en los casos de CL en todo el mundo.

Conclusiones:

  • A pesar de los avances en algunas áreas, el control de la leishmaniosis sigue siendo un desafío.
  • Las lagunas significativas en la evidencia y la necesidad de nuevas herramientas son fundamentales para el control definitivo.
  • Se necesitan con urgencia nuevos tratamientos y estrategias de control.