Video Experimental Relacionado

Updated: Feb 4, 2026

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis
09:32

Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis

Published on: October 15, 2021

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Presión evolutiva contra las mutaciones cancerígenas vinculantes de clase II del MHC

Rachel Marty Pyke1, Wesley Kurt Thompson2, Rany M Salem3

  • 1Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA 92093, USA; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA 92093, USA.

Cell
|September 25, 2018
PubMed
Resumen

Las células T CD4+ desempeñan un papel crucial en la inmunidad antitumoral al influir en la evolución del tumor. La presentación de MHC-II restringe las mutaciones cancerosas, afectando el desarrollo tumoral y destacando la importancia de las respuestas de las células T CD4+.

Palabras clave:
En el caso de las MHC-IICélulas Tel cáncermutaciones del controladorEdición inmuneImunidadinmunoterapiaEvolución del tumor

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