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Probing The Structure And Dynamics Of Nucleosomes Using Atomic Force Microscopy Imaging
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Bases estructurales de la transición del nucleosoma durante el paso de la ARN polimerasa II

Tomoya Kujirai1,2, Haruhiko Ehara2, Yuka Fujino1,3

  • 1Laboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.

Science (New York, N.Y.)
|October 6, 2018
PubMed
Resumen

Los investigadores visualizaron la ARN polimerasa II (RNAPII) transcribiendo el ADN dentro de los nucleosomas, revelando cómo la enzima se detiene y progresa. Estos hallazgos iluminan los mecanismos de transcripción de la cromatina y la regulación epigenética.

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