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Updated: Feb 4, 2026

Conditional Reprogramming of Pediatric Human Esophageal Epithelial Cells for Use in Tissue Engineering and Disease Investigation
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La reprogramación de los tejidos epiteliales humanos normales a un linaje de cáncer neuroendocrino común y letal

Jung Wook Park1, John K Lee2, Katherine M Sheu3

  • 1Department of Microbiology, Immunology, and Molecular Genetics, University of California-Los Angeles, Los Angeles, CA 90095, USA.

Science (New York, N.Y.)
|October 6, 2018
PubMed
Resumen

Las terapias potentes contra el cáncer pueden causar un carcinoma neuroendocrino de células pequeñas (SCNC) agresivo. Los investigadores encontraron factores comunes que reprograman las células normales al SCNC, lo que sugiere vulnerabilidades compartidas para el desarrollo de nuevos medicamentos.

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