Jove
Visualize
Contáctanos

Videos de Conceptos Relacionados

Generator Voltage Control01:21

Generator Voltage Control

660
Generator voltage control is crucial for maintaining the stable operation of synchronous generators and wind turbines. In older models, a DC generator driven by the rotor delivers DC power to the rotor's field winding, and the power is transferred through slip rings and brushes. In the latest models, static or brushless exciters are used. Static exciters rectify AC power from the generator terminals and then transfer the DC power directly to the rotor. Brushless exciters, on the other hand, use...
660
Synaptic Signaling01:12

Synaptic Signaling

79.5K
Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
79.5K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

9.9K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
9.9K
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

939
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
939
Plasticity00:58

Plasticity

3.1K
Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
3.1K
Plasticizers01:31

Plasticizers

368
Water-reducers, or plasticizers, are chemical admixtures used in concrete to improve strength and workability. These additives reduce the water-cement ratio without compromising workability, lower the cement content while maintaining the same workability, or increase workability to assist concrete placement in inaccessible areas.
Plasticizers function by using surface-active agents to create repulsive electrostatic forces between cement particles. This dispersion enhances the concrete's...
368

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Circadian rest/activity rhythms and change in MRI-derived brain volumes: Differences by age in a cognitively healthy sample.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Metaplastic sleep regulation in <i>Drosophila</i> determined by microscale circadian neural dynamics.

bioRxiv : the preprint server for biology·2026
Same author

Metaplastic neuronal state transition regulates species-specific interoceptive processing in <i>Drosophila</i>.

bioRxiv : the preprint server for biology·2026
Same author

Neuronal microscale biophysical instability mediates macroscale network dynamics shaping pathological manifestations.

bioRxiv : the preprint server for biology·2026
Same author

Integrative MultiOmics and Machine Learning Reveal Peroxiredoxin 4 as a Critical Hub Governing Mitochondrial Dysfunction and B Cell Differentiation in Periodontitis.

Clinical, cosmetic and investigational dentistry·2025
Same author

TrveA affects the pathogenicity to apples by regulating the sporulation, reactive oxygen species and trichothecenes metabolic pathways in Trichothecium roseum.

Food microbiology·2025
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
Ver todos los artículos relacionados
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Video Experimental Relacionado

Updated: Feb 4, 2026

3D Modeling of Dendritic Spines with Synaptic Plasticity
07:13

3D Modeling of Dendritic Spines with Synaptic Plasticity

Published on: May 18, 2020

7.4K

Los códigos temporales generados por el reloj determinan la plasticidad sináptica para controlar el sueño

Masashi Tabuchi1, Joseph D Monaco2, Grace Duan1

  • 1Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.

Cell
|October 16, 2018
PubMed
Resumen
Este resumen es generado por máquina.

Los patrones de picos temporales en las neuronas del reloj de Drosophila controlan la excitación y el sueño, independientemente de la velocidad de disparo. Este estudio identifica vías moleculares y demuestra la codificación temporal

Palabras clave:
Las Drosophilareloj circadianoel sueñoPlasticidad sinápticaCodificación temporal

Más Videos Relacionados

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
14:27

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Published on: August 11, 2019

13.5K
Noninvasive, High-throughput Determination of Sleep Duration in Rodents
07:33

Noninvasive, High-throughput Determination of Sleep Duration in Rodents

Published on: April 18, 2018

8.3K

Videos de Experimentos Relacionados

Last Updated: Feb 4, 2026

3D Modeling of Dendritic Spines with Synaptic Plasticity
07:13

3D Modeling of Dendritic Spines with Synaptic Plasticity

Published on: May 18, 2020

7.4K
Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
14:27

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Published on: August 11, 2019

13.5K
Noninvasive, High-throughput Determination of Sleep Duration in Rodents
07:33

Noninvasive, High-throughput Determination of Sleep Duration in Rodents

Published on: April 18, 2018

8.3K

Área de la Ciencia:

  • La neurociencia
  • Cronología
  • Biología molecular

Sus antecedentes:

  • Las neuronas codifican la información utilizando la codificación de velocidad (frecuencia de disparo) y la codificación temporal (tiempo de disparo / patrones).
  • Se debate la suficiencia de los códigos temporales por sí solos para el control del comportamiento y sus mecanismos moleculares subyacentes.

Objetivo del estudio:

  • Investigar si los patrones de picos temporales distintos, separados de la velocidad de disparo, codifican la excitación dependiente del tiempo y regulan el sueño en Drosophila.
  • Para identificar las vías moleculares responsables de la generación de patrones de picos temporales circadianos dependientes.

Principales métodos:

  • Utilizó neuronas de reloj de Drosophila para estudiar la codificación neuronal.
  • Se llevó a cabo una prueba genética a gran escala para identificar vías moleculares.
  • Investigó la morfología de los picos y los cambios en el flujo iónico.

Principales resultados:

  • Se demostró que distintos patrones de picos temporales, independientes de la velocidad de disparo, codifican la excitación dependiente del tiempo y regulan el sueño.
  • Caminos moleculares identificados que median el flujo iónico circadiano dependiente y los cambios en la morfología de los picos que modulan el tiempo de los picos.
  • Demostró que los patrones de picos diurnos por sí solos pueden inducir plasticidad en las neuronas de excitación aguas abajo.

Conclusiones:

  • La codificación temporal juega un papel causal en el comportamiento, específicamente en la regulación de la excitación y el sueño.
  • Definido una nueva forma de plasticidad sináptica provocada exclusivamente por patrones de picos temporales.
  • Mecanismos moleculares elucidados que subyacen a la generación de códigos temporales relevantes para el comportamiento.