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Purification and Visualization of Lipopolysaccharide from Gram-negative Bacteria by Hot Aqueous-phenol Extraction
05:31

Purification and Visualization of Lipopolysaccharide from Gram-negative Bacteria by Hot Aqueous-phenol Extraction

Published on: May 28, 2012

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Una nueva clase de antibacterianos sintéticos que actúan sobre la biosíntesis de los lipopolisacáridos

S M Hammond, A Claesson, A M Jansson

    Nature
    |June 1, 1987
    PubMed
    Resumen

    Los nuevos antimicrobianos sintéticos se dirigen a las bacterias gramnegativas al inhibir la biosíntesis de lipopolisacáridos. Un nuevo enfoque utiliza un análogo modificado de beta-KDO acoplado a un dipeptido para mejorar la entrada bacteriana y la muerte celular.

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