Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

From DNA to Protein03:06

From DNA to Protein

22.4K
The flow of genetic information in cells from DNA to mRNA to protein is described by the central dogma, which states that genes specify the sequence of mRNAs, which in turn specify the sequence of amino acids making up all proteins. The decoding of one molecule to another is performed by specific proteins and RNAs. Because the information stored in DNA is so central to cellular function, it makes intuitive sense that the cell would make mRNA copies of this information for protein synthesis...
22.4K
Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)01:16

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)

3.2K
Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...
3.2K
Actin Polymerization01:42

Actin Polymerization

8.6K
Actin polymerization occurs through the head-to-tail association of binding sites on monomeric actin or G-actin to form filamentous or F-actin. The polymerization can be divided into three phases ̶  nucleation, elongation, and steady-state phase.
The nucleation phase involves forming a stable nucleus consisting of three actin monomers to form a new actin filament. Actin-binding proteins such as formins and Arp2/3 complex help filament growth post-nucleation. The Formins form straight...
8.6K
Single-Strand DNA Binding Proteins01:03

Single-Strand DNA Binding Proteins

16.7K
For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
16.7K
DNA Helicases00:55

DNA Helicases

24.1K
DNA unwinding helicase enzymes are a type of motor protein. Motor proteins can translocate along filaments or polymers using energy generated from ATP hydrolysis. Helicases are involved in all the important cellular processes where DNA unwinding is required, such as DNA replication, repair, recombination, and transcription. They are present in all living organisms, but vary in their structure, function, and mechanism of action. For example, in prokaryotes, DnaB helicase binds and translocates...
24.1K
DNA Packaging00:58

DNA Packaging

112.6K
Overview
112.6K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Metal-Phenolic Coatings Enable Universal Design of Spherical Nucleic Acids.

Angewandte Chemie (International ed. in English)·2026
Same author

Correction to "DNA-Mediated Cellular Delivery of Functional Enzymes".

Journal of the American Chemical Society·2026
Same author

High-χ Block Copolymer Nanoreactors for the Confined Synthesis of Size-Controlled Nanoclusters.

ACS nano·2026
Same author

Programmable Stepwise Heteroepitaxial Growth of Colloidal Crystals With Different Phases.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Simplex-based model for nanoparticle grain identification in four-dimensional scanning transmission electron microscopy data.

Journal of microscopy·2026
Same author

Investigating the <i>In Vivo</i> Performance of Tannic Acid-Modified siRNA in the Heart and Liver.

Bioconjugate chemistry·2026
Same journal

Linker Engineering toward NIR-II Metal-Organic Framework with Maximal Emission beyond 1000 nm for Inflammatory Bowel Disease Imaging.

Journal of the American Chemical Society·2026
Same journal

Observing Kinetic Selectivity in Anthracene Photodimerization through Selective Quenching by Excited States of Proximate Rare Earth Cations.

Journal of the American Chemical Society·2026
Same journal

Sequence-Dependent Folding of Recognition-Encoded Melamine Oligomers.

Journal of the American Chemical Society·2026
Same journal

Large Thermo- and Mechanosalient Actuation via Cooperative Twist Elasticity-Induced Packing Motif Conversion.

Journal of the American Chemical Society·2026
Same journal

Discovery and Biosynthesis of Lanthipeptides Featuring an Azepinoindole Scaffold by Radical <i>S</i>-Adenosylmethionine Enzyme-Catalyzed C-C Bond Formation.

Journal of the American Chemical Society·2026
Same journal

Enantiopurity-Controlled Magnetism in a Two-Dimensional Organic-Inorganic Material.

Journal of the American Chemical Society·2026
Ver todos los artículos relacionados

Video Experimental Relacionado

Updated: Feb 2, 2026

Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles
09:01

Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles

Published on: September 27, 2013

11.6K

Programación de la polimerización de proteínas con el ADN

Janet R McMillan, Oliver G Hayes, Jonathan P Remis

    Journal of the American Chemical Society
    |November 9, 2018
    PubMed
    Resumen
    Este resumen es generado por máquina.

    Los investigadores desarrollaron una estrategia basada en el ADN para controlar las vías de polimerización de proteínas. Este método permite una programación precisa de la polimerización de crecimiento por etapas o por cadenas para crear nuevos materiales basados en proteínas.

    Más Videos Relacionados

    Visualization of Surface-tethered Large DNA Molecules with a Fluorescent Protein DNA Binding Peptide
    08:51

    Visualization of Surface-tethered Large DNA Molecules with a Fluorescent Protein DNA Binding Peptide

    Published on: June 23, 2016

    11.3K
    Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization
    07:28

    Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization

    Published on: November 27, 2015

    13.8K

    Videos de Experimentos Relacionados

    Last Updated: Feb 2, 2026

    Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles
    09:01

    Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles

    Published on: September 27, 2013

    11.6K
    Visualization of Surface-tethered Large DNA Molecules with a Fluorescent Protein DNA Binding Peptide
    08:51

    Visualization of Surface-tethered Large DNA Molecules with a Fluorescent Protein DNA Binding Peptide

    Published on: June 23, 2016

    11.3K
    Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization
    07:28

    Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization

    Published on: November 27, 2015

    13.8K

    Área de la Ciencia:

    • Ciencia de los biomateriales
    • Biología molecular
    • Química de los polímeros

    Sus antecedentes:

    • El autoensamblaje de las proteínas es crucial para las funciones biológicas.
    • El control de las vías de polimerización de proteínas es un desafío.
    • La programabilidad del ADN ofrece un nuevo enfoque para el ensamblaje directo de proteínas.

    Objetivo del estudio:

    • Desarrollar una estrategia mediada por el ADN para controlar la polimerización de proteínas.
    • Para lograr un control mecanicista sobre las vías de polimerización de crecimiento por etapas y por cadenas.
    • Para sintetizar oligómeros y polímeros basados en proteínas con arquitecturas controladas.

    Principales métodos:

    • Síntesis y caracterización de los monómeros de la proteína fluorescente verde mutante (mGFP) - ADN.
    • Utilizando interacciones de ADN específicas de la secuencia para programar barreras de energía de polimerización.
    • Microscopía criolectrónica con tecnología de placa de fase Volta para visualizar productos de ensamblaje.

    Principales resultados:

    • Capacidad demostrada para acceder a las vías de polimerización de crecimiento escalonado y de crecimiento en cadena mediante la modificación de secuencias y conformaciones de ADN.
    • Se han observado distintas distribuciones de polímeros (cíclica/lineal para el crecimiento escalonado, exclusivamente lineal para el crecimiento en cadena).
    • Mostró el carácter "vivo" del sistema de crecimiento de la cadena, lo que permite la extensión de la cadena.

    Conclusiones:

    • Estableció una metodología robusta para sintetizar materiales basados en proteínas con un control arquitectónico preciso.
    • Este trabajo representa un ejemplo temprano de control mecanicista sobre el ensamblaje de proteínas utilizando ADN.
    • La estrategia desarrollada permite la creación de nuevos materiales oligoméricos y poliméricos basados en proteínas.