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Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

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Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
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Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

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Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
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In-vitro Mutagenesis01:16

In-vitro Mutagenesis

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To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
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Crystal Field Theory - Tetrahedral and Square Planar Complexes02:46

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Tetrahedral Complexes
Crystal field theory (CFT) is applicable to molecules in geometries other than octahedral. In octahedral complexes, the lobes of the dx2−y2 and dz2 orbitals point directly at the ligands. For tetrahedral complexes, the d orbitals remain in place, but with only four ligands located between the axes. None of the orbitals points directly at the tetrahedral ligands. However, the dx2−y2 and dz2 orbitals (along the Cartesian axes) overlap with the ligands less than the dxy,...
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The Citric Acid Cycle02:36

The Citric Acid Cycle

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The citric acid cycle, also known as the Krebs cycle or TCA cycle, consists of several energy-generating reactions that yield one ATP molecule, three NADH molecules, one FADH2 molecule, and two CO2 molecules.
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Henderson-Hasselbalch Equation02:48

Henderson-Hasselbalch Equation

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The ionization-constant expression for a solution of a weak acid can be written as:
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Video Experimental Relacionado

Updated: Feb 1, 2026

Author Spotlight: A Novel 3D-Printed Titanium Implant for Minimally Invasive Treatment of Hip Dysplasia in Young Dogs
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Reemplazo de cadera

Rory J Ferguson1, Antony Jr Palmer1, Adrian Taylor1

  • 1Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

Lancet (London, England)
|November 30, 2018
PubMed
Resumen
Este resumen es generado por máquina.

La cirugía de reemplazo total de cadera maneja eficazmente el dolor de la artritis de cadera y mejora la función. Los factores del paciente, los avances de los implantes y los datos del registro son cruciales para los resultados exitosos y la toma de decisiones informadas en cirugía ortopédica.

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Área de la Ciencia:

  • Cirugía ortopédica
  • Ingeniería biomédica
  • Resultados informados por los pacientes

Sus antecedentes:

  • El reemplazo total de cadera (THR) es una cirugía común y exitosa para la artritis de cadera avanzada.
  • La osteoartritis es la indicación principal, lo que impulsa la necesidad de aliviar el dolor y mejorar la función.
  • Los implantes modernos se enfrentan a demandas crecientes debido al deseo de los pacientes de una vida activa más larga.

Objetivo del estudio:

  • Explorar cómo los factores específicos del paciente influyen en la toma de decisiones quirúrgicas en THR.
  • Revisar los avances en tecnología de implantes y cuidados perioperatorios que minimizan las complicaciones.
  • Discutir la importancia de las medidas de resultado informadas por los pacientes y de los datos del registro para evaluar el éxito de la THR.

Principales métodos:

  • Revisión de la literatura actual sobre THR, selección de pacientes y tecnología de implantes.
  • Análisis de los factores que influyen en los resultados quirúrgicos.
  • Examen de los datos de los registros de sustitución conjuntos y de los marcos reglamentarios.

Principales resultados:

  • Los factores del paciente influyen significativamente en la toma de decisiones y los resultados de la THR.
  • Los avances en los implantes y las prácticas perioperatorias han mejorado la seguridad y la eficacia de THR.
  • Los registros de reemplazo de articulaciones son vitales para monitorear la supervivencia de los implantes e informar sobre los cambios regulatorios.

Conclusiones:

  • Los enfoques quirúrgicos personalizados que consideran los factores del paciente son esenciales para el éxito de THR.
  • La innovación continua en implantes y técnicas quirúrgicas es necesaria para satisfacer las expectativas de los pacientes.
  • El fortalecimiento de la supervisión reguladora, basada en los datos del registro, es fundamental para la seguridad de los pacientes en THR.