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Updated: Feb 1, 2026

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Control espacio-temporal de la mielinización del SNC por la muerte celular programada por oligodendrocitos a través

Lu O Sun1, Sara B Mulinyawe1, Hannah Y Collins1

  • 1Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Cell
|December 4, 2018
PubMed
Resumen

El factor de transcripción EB (TFEB) controla el tiempo de mielinización del sistema nervioso central (SNC). La pérdida de TFEB conduce a la mielinización prematura, revelando un mecanismo molecular clave para el desarrollo de oligodendrocitos y la escultura de mielina.

Palabras clave:
Sistema nervioso centralPUMA y sus derivadosLa mielinizaciónOligodendrocitomuerte celular programadarespuesta al estrésEspecificidad temporal y regionalFactor de transcripción EB

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