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Diseño racional de un emulsionador de coordinación anfifílico basado en jaula

Subhadeep Saha¹, Björn Holzapfel¹, Yen-Ting Chen²

¹Faculty of Chemistry and Chemical Biology , TU Dortmund University , Otto-Hahn-Str. 6 , 44227 Dortmund , Germany.

Journal of the American Chemical Society

|December 6, 2018

Resumen

Los investigadores crearon nuevos anfífilos gemelos basados en jaulas (CGAs) que se autoensamblan en vesículas. Estas estructuras pueden formar cadenas y estabilizar las emulsiones de aceite en aceite, expandiendo las aplicaciones para las jaulas de coordinación porosas.

Área de la Ciencia:

Química supramolecular
Ciencias de los materiales
Nanotecnología

Sus antecedentes:

Las jaulas de coordinación porosas permiten la inclusión controlada del huésped, la administración de fármacos, la separación y la catálisis.
Existe una investigación limitada sobre el uso de la forma de jaula 3D y la funcionalidad externa para materiales autoensamblados.

Objetivo del estudio:

Desarrollar nuevos materiales autoensamblados a partir de jaulas de coordinación funcionales.
Para investigar el comportamiento de auto-ensamblaje y las propiedades de las anfifilas Gemini basadas en jaulas.

Principales métodos:

Síntesis de ligandos basados en acridona (L^A) y derivados del fenantreno (L^B).
Autoensamblaje de ligandos en jaulas de coordinación heterolépticas cis-[Pd2(L^A) 2 ((L^B) 2) 4+ (CGA-1).
Caracterización mediante el uso de cryo-TEM y microscopía electrónica de transmisión de células líquidas (LC-TEM).

Principales resultados:

Las jaulas catiónicas (CGA-1) con cadenas laterales anisotrópicas se autoensamblan en vesículas (> 100 nm de diámetro) en disolventes polares.
El LC-TEM mostró vesículas formando cadenas y collares a través de interacciones de largo alcance.
Las jaulas demostraron una capacidad para estabilizar las emulsiones de aceite en aceite.

Conclusiones:

Los anfífilos geminicos basados en jaulas (CGAs) pueden formar estructuras vesiculares autoensambladas.
Estos AGC exhiben comportamientos únicos de agregación y capacidades de estabilización de la emulsión.
Los resultados amplían la utilidad de las jaulas de coordinación en la ciencia de los materiales y la nanotecnología.

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