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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

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Desregulación del nivel de la isoforma en todo el transcriptoma en TEA, esquizofrenia y trastorno bipolar

Michael J Gandal, Pan Zhang, Evi Hadjimichael

    Science (New York, N.Y.)
    |December 15, 2018
    PubMed
    Resumen

    El riesgo genético de trastornos psiquiátricos como el trastorno del espectro autista (TEA), la esquizofrenia y el trastorno bipolar afecta significativamente la expresión genética y el empalme. Este estudio revela cambios transcriptómicos generalizados e identifica nuevos mecanismos neural-inmunes.

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