Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Eukaryotic Compartmentalization01:37

Eukaryotic Compartmentalization

18.2K
One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles, such as the nucleus and mitochondria, that carry out specialized functions. Since biological membranes are only selectively permeable to solutes, they help create a compartment with controlled conditions inside an organelle. These microenvironments are tailored to the organelle's specific functions and help isolate them from the surrounding cytosol.
For example, lysosomes in the animal...
18.2K
Eukaryotic Compartmentalizations01:46

Eukaryotic Compartmentalizations

174.6K
One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles, such as the nucleus and mitochondria, that carry out specialized functions. Since biological membranes are only selectively permeable to solutes, they help create a compartment with controlled conditions inside an organelle. These microenvironments are tailored to the organelle's specific functions and help isolate them from the surrounding cytosol.
For example, lysosomes in the animal cells...
174.6K
Mitochondrial Protein Sorting01:39

Mitochondrial Protein Sorting

5.8K
Mitochondria are double-membrane organelles of the eukaryotes involved in cellular metabolism, signaling, ATP synthesis, and programmed cell death.  Each of these processes requires specific proteins and enzymes that must be correctly sorted to the right mitochondrial subcompartment for the proper functioning of the organelle.
Most of these mitochondrial proteins are encoded by the nucleus and imported to the mitochondria as unfolded or loosely folded precursors. Mitochondrial precursors...
5.8K
Nuclear Protein Sorting01:34

Nuclear Protein Sorting

6.4K
Nuclear protein sorting is the selective trafficking of histones, polymerases, gene regulatory proteins into the nucleus and exporting RNAs and ribosomes to the cytosol. It is a tightly controlled process that regulates gene expression within a cell.
Proteins targeted to the nucleus carry nuclear localization signals or NLS recognized by import receptors in the cytosol. Similarly, proteins with nuclear export signals are recognized by export receptors. Import and export receptors are...
6.4K
Two-dimensional Gel Electrophoresis01:22

Two-dimensional Gel Electrophoresis

7.5K
Two-dimensional gel electrophoresis is a high-resolution protein separation method first introduced by O' Farrell and Klose in 1975. This method involves protein separation by two dimensions, mass and charge, making it more accurate than one-dimensional gel electrophoresis.
The first dimension separation uses the isoelectric focusing or IEF technique performed on immobilized pH gradient (IPG) strips that separate proteins according to their isoelectric points.
Biological samples, such...
7.5K
Overview of Protein Sorting and Transport01:45

Overview of Protein Sorting and Transport

22.9K
Eukaryotic cells have different membrane-bound organelles with distinct protein requirements. The process by which proteins are targeted to a specific organelle is called protein sorting.
Protein sorting can be of two types: signal-based sorting and vesicle-based trafficking. In signal-based sorting, specific amino acid sequences called sorting signals target proteins to the proper location inside the cell either via gated transport or by protein translocation.  In gated transport, folded...
22.9K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Light-switchable enzyme-mimetic organocatalysis in water via supramolecular assembly.

Communications chemistry·2026
Same author

Tuning the size and defect chemistry of TiO<sub>2</sub><i>via</i> flash nanoprecipitation for enhanced photocatalytic antibacterial activity.

Nanoscale·2026
Same author

Mechano-Electrochemical Coupling Enabled by Triple-Gradient Interface Engineered Garnet for Durable All-Solid-State Lithium Metal Batteries.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Sortase A-Mediated Farnesylation of Cdc42 <i>In Vitro</i>.

ACS synthetic biology·2026
Same author

Multicomponent Polymer Network Immobilizing MoS<sub>2</sub> Nanosheets for Stable Hg<sup>2+</sup> Capture under Competitive Ion Conditions.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Fabrication of Hierarchically Structured Free-Standing Supramolecular Hydrogels through Flow-Driven Reaction-Diffusion.

Small (Weinheim an der Bergstrasse, Germany)·2026

Video Experimental Relacionado

Updated: Jan 31, 2026

Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

10.5K

Geles supramoleculares compartimentados jerárquicamente a través de la autoclasificación en varios niveles

Yiming Wang1, Matija Lovrak1, Qian Liu1

  • 1Department of Chemical Engineering , Delft University of Technology , van der Maasweg 9 , 2629 HZ Delft , The Netherlands.

Journal of the American Chemical Society
|December 20, 2018
PubMed
Resumen

Los científicos crearon geles supramoleculares que se clasifican por sí mismos, imitando la compartimentación celular. Este enfoque de abajo hacia arriba permite la formación espontánea de materiales funcionales estructurados jerárquicamente a partir de bloques de construcción simples.

Más Videos Relacionados

Hierarchical and Programmable One-Pot Oligosaccharide Synthesis
09:56

Hierarchical and Programmable One-Pot Oligosaccharide Synthesis

Published on: September 6, 2019

7.3K
Versatile Technique to Produce a Hierarchical Design in Nanoporous Gold
05:28

Versatile Technique to Produce a Hierarchical Design in Nanoporous Gold

Published on: February 10, 2023

2.2K

Videos de Experimentos Relacionados

Last Updated: Jan 31, 2026

Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

10.5K
Hierarchical and Programmable One-Pot Oligosaccharide Synthesis
09:56

Hierarchical and Programmable One-Pot Oligosaccharide Synthesis

Published on: September 6, 2019

7.3K
Versatile Technique to Produce a Hierarchical Design in Nanoporous Gold
05:28

Versatile Technique to Produce a Hierarchical Design in Nanoporous Gold

Published on: February 10, 2023

2.2K

Área de la Ciencia:

  • Química supramolecular
  • Ciencias de los materiales
  • Biología sintética

Sus antecedentes:

  • La compartimentación jerárquica es crucial para la función celular, pero es difícil de replicar en sistemas sintéticos.
  • Los enfoques de abajo hacia arriba ofrecen una vía para crear estructuras celulares complejas.

Objetivo del estudio:

  • Desarrollar géis supramoleculares compartimentados jerárquicamente utilizando una estrategia de abajo hacia arriba.
  • Investigar la autoclasificación espontánea en varios niveles para la fabricación de materiales.

Principales métodos:

  • Formación in situ de dos geladores moleculares distintos a partir de bloques de construcción sin ensamblar.
  • Auto-clasificación cinética de las fibras de gel en microdominios separados.
  • Caracterización de las redes de gel compartimentadas a microescala resultantes.

Principales resultados:

  • Se han formado con éxito geles supramoleculares compartimentados jerárquicamente.
  • Se ha demostrado la autoclasificación espontánea en varios niveles de las fibras de gel.
  • Se logró la compartimentación a microescala a través de la autoclasificación.

Conclusiones:

  • La autoclasificación espontánea de varios niveles proporciona un enfoque viable de abajo hacia arriba para crear materiales funcionales estructurados jerárquicamente.
  • Estos sistemas ofrecen información sobre la organización intracelular y las aplicaciones potenciales en biología sintética.