Video Experimental Relacionado
Updated: Jan 29, 2026
08:42
Microfluidic-based Synthesis of Covalent Organic Frameworks COFs: A Tool for Continuous Production of COF Fibers and Direct Printing on a Surface
Published on: July 10, 2017
14.1K
Las estructuras orgánicas covalentes tridimensionales basadas en salfeno como antioxidantes catalíticos
Shichen Yan1, Xinyu Guan1, Hui Li1
1State Key Laboratory of Inorganic Synthesis and Preparative Chemistry , Jilin University , Changchun 130012 , P. R. China.
Journal of the American Chemical Society
|February 6, 2019
Resumen
Los investigadores desarrollaron nuevos marcos orgánicos covalentes funcionalizados en 3D (COF) utilizando ligandos de Salphen. Estos materiales avanzados son prometedores para aplicaciones en biología y medicina, particularmente en la eliminación de radicales superóxidos dañinos.
Área de la Ciencia:
- Ciencias de los materiales
- Química
- Nanotecnología
Sus antecedentes:
- Los marcos orgánicos covalentes tridimensionales (3D) son cruciales para las aplicaciones avanzadas.
- La funcionalidad de los COF 3D es un área poco explorada.
- Los ligandos a base de salfeno ofrecen propiedades únicas para la construcción del marco.
Objetivo del estudio:
- Informar sobre la primera síntesis de COFs 3D basados en salfeno y sus análogos que contienen metales.
- Investigar las propiedades y aplicaciones potenciales de estos nuevos COF 3D.
- Establecer un nuevo método para la creación de COF funcionales en 3D.
Principales métodos:
- Síntesis de COF basados en salfeno en 3D (3D-salfeno-COF).
- Preparación de 3D-Salfen-COFs que contienen metales (3D-M-Salfen-COFs).
- Caracterización de la cristalinidad, la superficie y la estabilidad química.
- Evaluación de la actividad de eliminación de radicales de superóxido.
Principales resultados:
- Síntesis exitosa de 3D-Salfen-COFs y 3D-M-Salfen-COFs de alta cristalinidad.
- Se ha demostrado una excelente estabilidad química y una gran superficie específica.
- El COF de cobre-salfeno mostró una actividad significativa en la eliminación de los radicales de superóxido.
- Se estableció una nueva ruta sintética para los COF 3D funcionalizados.
Conclusiones:
- Este trabajo introduce una nueva clase de COF funcionalizados en 3D.
- Los 3D-Salphen-COF desarrollados poseen propiedades materiales deseables.
- Los hallazgos sugieren aplicaciones potenciales en campos biológicos y médicos, particularmente para el manejo del estrés oxidativo.
Videos de Conceptos Relacionados
02:18Network Covalent Solids
16.2K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
16.2K
01:29Covalent Bonds
161.9K
Overview
161.9K
01:08Covalent Bonds
10.7K
Overview
When two atoms share electrons to complete their valence shells, they create a covalent bond. An atom's electronegativity—the force with which shared electrons are pulled towards an atom—determines how the electrons are shared. Molecules formed with covalent bonds can be either polar or nonpolar. Atoms with similar electronegativities form nonpolar covalent bonds; the electrons are shared equally. Atoms with different electronegativities share electrons unequally,...
When two atoms share electrons to complete their valence shells, they create a covalent bond. An atom's electronegativity—the force with which shared electrons are pulled towards an atom—determines how the electrons are shared. Molecules formed with covalent bonds can be either polar or nonpolar. Atoms with similar electronegativities form nonpolar covalent bonds; the electrons are shared equally. Atoms with different electronegativities share electrons unequally,...
10.7K
02:04Covalently Linked Protein Regulators
9.5K
Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein....
These groups modify specific amino acids in a protein....
9.5K
02:46Covalent Bonding and Lewis Structures
61.3K
Compared to ionic bonds, which results from the transfer of electrons between metallic and nonmetallic atoms, covalent bonds result from the mutual attraction of atoms for a “shared” pair of electrons.
61.3K
01:19Turnover Number and Catalytic Efficiency
21.5K
The turnover number of an enzyme is the maximum number of substrate molecules it can transform per unit time. Turnover numbers for most enzymes range from 1 to 1000 molecules per second. Catalase has the known highest turnover number, capable of converting up to 2.8×106 molecules of hydrogen peroxide into water and oxygen per second. Lysozyme has the lowest known turnover number of half a molecule per second.
Chymotrypsin is a pancreatic enzyme that breaks down proteins during digestion....
Chymotrypsin is a pancreatic enzyme that breaks down proteins during digestion....
21.5K