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A algunos les gusta la transferencia horizontal de operones

Amelia R I Lindsey1, Irene L G Newton1

  • 1Department of Biology, Indiana University, Bloomington, IN 47405, USA.

Cell
|March 9, 2019
PubMed
Resumen
Este resumen es generado por máquina.

Se descubrió un raro evento de transferencia horizontal de operones (HOT) en las levaduras, que les permite adquirir hierro utilizando genes bacterianos. Este hallazgo arroja luz sobre el papel significativo de la transferencia horizontal de genes en la evolución eucariota.

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Área de la Ciencia:

  • Biología evolutiva
  • La genética
  • Microbiología

Sus antecedentes:

  • La transferencia horizontal de genes (HGT) se estudia ampliamente en las bacterias.
  • La prevalencia y el impacto de la HGT en los eucariotas no se conocen bien.

Objetivo del estudio:

  • Investigar la ocurrencia y la importancia de la transferencia horizontal de genes (HGT) en los eucariotas.
  • Identificar y caracterizar los eventos específicos de HGT que confieren ventajas adaptativas.

Principales métodos:

  • Análisis de datos genómicos para detectar eventos de transferencia de genes.
  • Análisis filogenético para trazar el origen de los genes transferidos.
  • Evidencia de selección para facilitar la expresión génica.

Principales resultados:

  • Identificación de un evento de transferencia horizontal de operones (HOT) en un grupo de levaduras.
  • El operón transferido contiene genes derivados de bacterias.
  • La evidencia sugiere que la selección favoreció la expresión de estos genes.

Conclusiones:

  • La transferencia horizontal de genes, específicamente la transferencia horizontal de operones (HOT), juega un papel en la evolución eucariota.
  • La adquisición de genes derivados de bacterias a través de HGT puede proporcionar ventajas adaptativas significativas, como una mayor eliminación de hierro en las levaduras.