Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

8.0K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
8.0K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

3.4K
3.4K
Classification of Skeletal Muscle Fibers01:48

Classification of Skeletal Muscle Fibers

59.4K
Skeletal muscles continuously produce ATP to provide the energy that enables muscle contractions. Skeletal muscle fibers can be categorized into three types based on differences in their contraction speed and how they produce ATP, as well as physical differences related to these factors. Most human muscles contain all three muscle fiber types, albeit in varying proportions.
Slow-Twitch Muscle Fibers
Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...
59.4K
Hormonal Regulation01:40

Hormonal Regulation

47.8K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
47.8K
Nuclear Fission02:50

Nuclear Fission

12.3K
Many heavier elements with smaller binding energies per nucleon can decompose into more stable elements that have intermediate mass numbers and larger binding energies per nucleon—that is, mass numbers and binding energies per nucleon that are closer to the “peak” of the binding energy graph near 56. Sometimes neutrons are also produced. This decomposition of a large nucleus into smaller pieces is called fission. The breaking is rather random with the formation of a large...
12.3K
Feedback Inhibition00:46

Feedback Inhibition

56.9K
Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
56.9K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Epigenetic control of p53 activity in regulatory T cells maintains their identity to prevent inflammation.

Journal of immunology (Baltimore, Md. : 1950)·2026
Same author

PRDM3 and PRDM16 define cranial neural crest cell states in zebrafish development.

bioRxiv : the preprint server for biology·2026
Same author

Stress Granule Sequestration of CCR4-NOT Promotes Poly(A) Lengthening of Stress-Survival Transcripts.

bioRxiv : the preprint server for biology·2026
Same author

The generation and consequences of N-terminal proteoform diversity.

Cell reports·2026
Same author

Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genes.

Molecular cell·2026
Same author

Divergent condensates tune transcriptional responses during stress.

bioRxiv : the preprint server for biology·2026

Video Experimental Relacionado

Updated: Jan 21, 2026

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model
10:58

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model

Published on: August 29, 2013

11.6K

Reduzca la velocidad para ponerse al día

Sujatha Jagannathan1, Srinivas Ramachandran1, Olivia S Rissland1

  • 1RNA Bioscience Initiative and Department of Biochemistry & Molecular Genetics, University of Colorado School of Medicine, Aurora, CO 80045, USA.

Cell
|August 10, 2019
PubMed
Resumen
Este resumen es generado por máquina.

El metabolismo lento puede suprimir los problemas de desarrollo causados por la pérdida de represores como los microARN en las moscas de la fruta. Este estudio revela el mecanismo que vincula el estado metabólico con los resultados del desarrollo.

Más Videos Relacionados

Fabrication And Characterization Of Photonic Crystal Slow Light Waveguides And Cavities
11:08

Fabrication And Characterization Of Photonic Crystal Slow Light Waveguides And Cavities

Published on: November 30, 2012

19.5K
Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

10.5K

Videos de Experimentos Relacionados

Last Updated: Jan 21, 2026

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model
10:58

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model

Published on: August 29, 2013

11.6K
Fabrication And Characterization Of Photonic Crystal Slow Light Waveguides And Cavities
11:08

Fabrication And Characterization Of Photonic Crystal Slow Light Waveguides And Cavities

Published on: November 30, 2012

19.5K
Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

10.5K

Área de la Ciencia:

  • Biología del desarrollo
  • Investigación del metabolismo
  • La genética

Sus antecedentes:

  • Los microARN son reguladores cruciales de la expresión génica, y su pérdida puede conducir a anormalidades del desarrollo.
  • Se sabe que el estado metabólico influye en varios procesos celulares, pero su papel directo en la supresión de defectos del desarrollo es menos entendido.

Objetivo del estudio:

  • Investigar la relación entre la tasa metabólica y las anomalías del desarrollo en Drosophila melanogaster.
  • Aclarar los mecanismos moleculares que conectan el estado metabólico con los resultados del desarrollo después de la pérdida de moléculas represoras.

Principales métodos:

  • Utilizando Drosophila melanogaster como un organismo modelo.
  • El uso de manipulación genética para alterar los niveles de represores (por ejemplo, microARN).
  • Manipulación de la tasa metabólica a través de intervenciones dietéticas o genéticas.
  • Analizando fenotipos de desarrollo y vías moleculares.

Principales resultados:

  • La pérdida de moléculas represoras, como los microARN, conduce a anormalidades de desarrollo en las moscas de la fruta.
  • Un ritmo metabólico más lento suprime significativamente estas anomalías del desarrollo.
  • El estudio identifica vías moleculares específicas a través de las cuales el estado metabólico influye en las trayectorias de desarrollo.

Conclusiones:

  • La tasa metabólica es un factor crítico que puede modular las consecuencias fenotípicas de la regulación genética alterada.
  • La orientación de las vías metabólicas puede ofrecer nuevas estrategias para corregir los defectos de desarrollo derivados de la desregulación genética.