Jove
Visualize
Contáctanos

Videos de Conceptos Relacionados

The Resting Membrane Potential01:21

The Resting Membrane Potential

141.9K
Overview
141.9K
Resting Potential Decay01:15

Resting Potential Decay

6.2K
The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps.
At rest, the K+ is the main ion that moves across the membrane...
6.2K
Resting Membrane Potential01:24

Resting Membrane Potential

21.4K
The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane.
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
21.4K
Voltage01:13

Voltage

3.8K
The movement of electrons in a conductor requires some form of energy or work, usually provided by an external force, like a battery. This force is called the electromotive force or voltage. The voltage between two points, referred to as points "a" and "b," in an electric circuit is the energy (or work) needed to move a unit charge from point "a" to point "b," and this relationship is expressed mathematically as
3.8K
The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

The Sense of Self: Reflected Self-Appraisal and Social Comparison

55.4K
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
55.4K
Pressure Variation in a Fluid at Rest01:11

Pressure Variation in a Fluid at Rest

747
In a fluid at rest, the pressure at any point beneath the fluid surface depends solely on the depth, not on the container's shape or size. This principle, known as hydrostatic pressure, arises because, in stationary fluids, there is no acceleration, meaning the forces within the fluid balance out. Only vertical forces, caused by the weight of the fluid above, contribute to pressure changes with depth.
When measuring pressure at two different levels within the fluid, the difference in...
747

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Senotoxins target senescence via lipid binding specificity, ion imbalance and lipidome remodeling.

Nature aging·2026
Same author

One-shot design elevates functional expression levels of a voltage-gated potassium channel.

Protein science : a publication of the Protein Society·2024
Same author

Understanding the Molecular Regulation of Serotonin Receptor 5-HTR<sub>1B</sub>-β-Arrestin1 Complex in Stress and Anxiety Disorders.

Journal of molecular neuroscience : MN·2023
Same author

Store-operated Ca<sup>2+</sup> entry regulatory factor alters murine metabolic state in an age-dependent manner via hypothalamic pathways.

PNAS nexus·2023
Same author

Modern venomics-Current insights, novel methods, and future perspectives in biological and applied animal venom research.

GigaScience·2022
Same author

Production of recombinant venom peptides as tools for ion channel research.

Methods in enzymology·2021
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
Same journal

Systematic discovery of pathogen effector functions across human pathogens and pathways.

Cell·2026
Same journal

Structural basis for host membrane binding and remodeling by invading malaria parasites.

Cell·2026
Same journal

Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning.

Cell·2026
Same journal

Arc mediates intercellular tau transmission via extracellular vesicles.

Cell·2026
Same journal

Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression.

Cell·2026
Ver todos los artículos relacionados
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Video Experimental Relacionado

Updated: Jan 21, 2026

Application of Voltage in Dynamic Light Scattering Particle Size Analysis
07:51

Application of Voltage in Dynamic Light Scattering Particle Size Analysis

Published on: January 24, 2020

10.4K

La detección de voltaje se detiene

Izhar Karbat1, Eitan Reuveny1

  • 1Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.

Cell
|August 10, 2019
PubMed
Resumen
Este resumen es generado por máquina.

Investigadores revelan la estructura de un canal de sodio controlado por voltaje en su estado de reposo. Esto proporciona información crucial sobre cómo se generan y propagan las señales eléctricas en las células.

Más Videos Relacionados

Virtual Hand with Ambiguous Movement between the Self and Other Origin: Sense of Ownership and 'Other-Produced' Agency
08:01

Virtual Hand with Ambiguous Movement between the Self and Other Origin: Sense of Ownership and 'Other-Produced' Agency

Published on: October 28, 2020

6.0K
Measuring the Induced Membrane Voltage with Di-8-ANEPPS
05:52

Measuring the Induced Membrane Voltage with Di-8-ANEPPS

Published on: November 19, 2009

18.0K

Videos de Experimentos Relacionados

Last Updated: Jan 21, 2026

Application of Voltage in Dynamic Light Scattering Particle Size Analysis
07:51

Application of Voltage in Dynamic Light Scattering Particle Size Analysis

Published on: January 24, 2020

10.4K
Virtual Hand with Ambiguous Movement between the Self and Other Origin: Sense of Ownership and 'Other-Produced' Agency
08:01

Virtual Hand with Ambiguous Movement between the Self and Other Origin: Sense of Ownership and 'Other-Produced' Agency

Published on: October 28, 2020

6.0K
Measuring the Induced Membrane Voltage with Di-8-ANEPPS
05:52

Measuring the Induced Membrane Voltage with Di-8-ANEPPS

Published on: November 19, 2009

18.0K

Área de la Ciencia:

  • Biología molecular
  • La biofísica
  • Fisiología celular

Sus antecedentes:

  • La detección de tensión por canales iónicos es fundamental para la actividad eléctrica en células excitables.
  • Comprender los estados conformacionales de estos canales es clave para descifrar la señalización eléctrica celular.

Objetivo del estudio:

  • Proporcionar una vista estructural de alta resolución de un canal de sodio regulado por tensión.
  • Para dilucidar la conformación cerrada en reposo de este canal iónico crítico.

Principales métodos:

  • Es probable que se haya empleado cristalografía de rayos X o microscopía cryoelectrónica (Cryo-EM).
  • Se utilizaron técnicas de análisis estructural y modelado molecular.

Principales resultados:

  • Se determinó un modelo atómico detallado del canal de sodio regulado por tensión en su estado cerrado.
  • Se identificaron las principales características estructurales que estabilizan la conformación en reposo.

Conclusiones:

  • La estructura determinada ofrece una base molecular para los mecanismos de detección de voltaje.
  • Esta visión estructural avanza nuestra comprensión de la iniciación y propagación de señales eléctricas en las neuronas y las células musculares.