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Videos de Conceptos Relacionados

Phylogeny01:23

Phylogeny

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Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
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Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface08:26

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface

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In this article, we describe a protocol for fabricating an amelogenin-chitosan hydrogel for superficial enamel reconstruction. Organized in situ growth of apatite crystals in the hydrogel formed a dense enamel-restoration interface, which will improve the effectiveness and durability of...
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Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants08:12

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

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Understanding enamel formation and possible alterations requires the study of ameloblast activity. Here, we describe a reliable and consistent method to micro-dissect enamel organs containing secretion- and maturation-stage ameloblasts that may be used for further quantitative and qualitative experimental...
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Sampling and Pretreatment of Tooth Enamel Carbonate for Stable Carbon and Oxygen Isotope Analysis07:57

Sampling and Pretreatment of Tooth Enamel Carbonate for Stable Carbon and Oxygen Isotope Analysis

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Stable carbon and oxygen isotope analysis of human and animal tooth enamel carbonate has been used as a proxy for individual diet and environmental reconstruction. Here, we provide a detailed description and visual documentation of bulk and sequential tooth enamel sampling as well as pretreatment of archaeological and paleontological...
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Laser Microdissection-Based Protocol for the LC-MS/MS Analysis of the Proteomic Profile of Neuromelanin Granules07:35

Laser Microdissection-Based Protocol for the LC-MS/MS Analysis of the Proteomic Profile of Neuromelanin Granules

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A robust protocol is presented here for isolating neuromelanin granules from human post-mortem substantia nigra pars compacta tissue via laser microdissection. This revised and optimized protocol massively minimizes the required time for sample collection, reduces the required sample amount, and enhances the identification and quantification of proteins by LC-MS/MS...
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Proteomic Sample Preparation from Formalin Fixed and Paraffin Embedded Tissue09:20

Proteomic Sample Preparation from Formalin Fixed and Paraffin Embedded Tissue

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Archival formalin fixed and paraffin embedded (FFPE) clinical samples are valuable material for investigation of diseases. Here we demonstrate a sample preparation workflow allowing in-depth proteomic analysis of microdissected FFPE...
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  1. Home
  2. El Proteoma Del Esmalte Del Pleistoceno Temprano De Dmanisi Resuelve La Filogenia De Stephanorhinus
  1. Home
  2. El Proteoma Del Esmalte Del Pleistoceno Temprano De Dmanisi Resuelve La Filogenia De Stephanorhinus

Video Experimental Relacionado

Phylogeny: Ancestral Relationships between Organisms
01:23

Phylogeny: Ancestral Relationships between Organisms

Published on: October 23, 2025

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El proteoma del esmalte del Pleistoceno temprano de Dmanisi resuelve la filogenia de Stephanorhinus

Enrico Cappellini1,2, Frido Welker3,4, Luca Pandolfi5

  • 1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark. ecappellini@bio.ku.dk.

Nature
|September 13, 2019

Ver abstracta en PubMed

Resumen
Este resumen es generado por máquina.

Las proteínas antiguas de los dientes de rinoceronte de 1.77 millones de años revelan nuevas ideas evolutivas. Este análisis proteómico empuja la reconstrucción de la evolución molecular más atrás de lo que permite el ADN antiguo.

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Área de la Ciencia:

  • La paleoproteomía
  • Evolución molecular
  • Filogenética

Sus antecedentes:

  • La secuenciación del ADN antiguo (ADN) ha revolucionado la comprensión de las especies extintas, pero está limitada por la degradación, típicamente a 0,5 millones de años.
  • La secuenciación de proteínas, utilizando métodos como la espectrometría de masa en tándem, ha analizado muestras más antiguas (por ejemplo, 1,5 millones de años), pero con una utilidad filogenética limitada.
  • Las relaciones evolutivas de muchas especies extintas del Pleistoceno temprano y medio siguen sin estar claras debido a la falta de evidencia molecular.