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Updated: Jan 2, 2026

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
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Descubrimiento de biomoléculas con actividad de Huisgenasa: Proteínas de repetición diseñadas como biocatalizadores

Iván Rivilla1, Mikel Odriozola-Gimeno1, Antonio Aires2

  • 1Department of Organic Chemistry I, Centro de Innovación en Química Avanzada (ORFEO-CINQA) , Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU) and Donostia International Physics Center (DIPC) , P° Manuel Lardizabal 3 , E-20018 Donostia/San Sebastián , Spain.

Journal of the American Chemical Society
|December 13, 2019
PubMed
Resumen

Las proteínas diseñadas, llamadas Huisgenasas, catalizan reacciones no naturales de 1,3-dipolar, creando nuevos ésteres de nitroprolina. Estas proteínas ofrecen un control preciso sobre los resultados de la reacción, lo que demuestra una nueva frontera en el biocatálisis.

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