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Updated: Dec 30, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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SnapShot: Alteraciones de empalme en el cáncer

Mohammad Alinoor Rahman1, Adrian R Krainer1, Omar Abdel-Wahab2

  • 1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

Cell
|January 18, 2020
PubMed
Resumen

Las células cancerosas alteran el empalme del ARN, el proceso de convertir el ARN pre-mensajero (pre-ARNm) en ARNm maduro. Las mutaciones interrumpen el empalme, lo que lleva a cambios específicos del tumor y afecta el desarrollo del cáncer.

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