Video Experimental Relacionado

Updated: Dec 28, 2025

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding

Published on: June 9, 2017

16.9K

Mecanismo molecular de la señalización sesgada en un receptor prototípico acoplado a proteínas G

Carl-Mikael Suomivuori1,2,3,4, Naomi R Latorraca1,2,3,4,5, Laura M Wingler6,7

  • 1Department of Computer Science, Stanford University, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|February 22, 2020
PubMed
Resumen

La señalización sesgada en los receptores acoplados a la proteína G ofrece nuevas posibilidades farmacológicas. Este estudio revela el mecanismo estructural detrás de la señalización sesgada en el receptor de angiotensina II tipo 1, lo que permite el diseño de terapias dirigidas.

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