Trombosis venosa profunda en pacientes hospitalizados con COVID-19 en Wuhan, China: Prevalencia, factores de riesgo y resultado
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Ver abstracta en PubMed
Resumen
Este resumen es generado por máquina.La trombosis venosa profunda (TVP) afecta a casi la mitad de los pacientes hospitalizados con COVID-19, lo que aumenta el riesgo de mortalidad. La profilaxis temprana puede beneficiar a las personas de alto riesgo, lo que sugiere que el COVID-19 es un factor de riesgo independiente de TVP.
Área De La Ciencia
- La medicina
- Enfermedades infecciosas
- Cardiología
Sus Antecedentes
- La trombosis venosa profunda (TVP) es una preocupación grave en los pacientes hospitalizados.
- La prevalencia y los factores de riesgo de TVP en pacientes con enfermedad por coronavirus 2019 (COVID-19) requieren una investigación adicional.
Objetivo Del Estudio
- Para determinar la prevalencia de TVP en pacientes hospitalizados con COVID-19.
- Identificar los factores de riesgo, el pronóstico y las estrategias efectivas de tromboprofilaxis para la TVP en esta población.
Principales Métodos
- Se realizó un estudio institucional único en 143 pacientes hospitalizados con COVID-19.
- Se recopilaron datos demográficos, clínicos y de laboratorio, incluidas ecografías de las extremidades inferiores.
- Se realizaron comparaciones entre pacientes con y sin TVP.
Principales Resultados
- La prevalencia de TVP en las extremidades inferiores fue del 46,1% (66/ 143 pacientes).
- Los pacientes con TVP eran mayores, tenían una menor oxigenación, mayores tasas de lesiones cardíacas y peores resultados (aumento de la mortalidad, disminución de las tasas de alta).
- Los factores de riesgo independientes para la TVP incluyen puntuación CURB-65 ≥3, puntuación de predicción Padua ≥4 y D-dimer >1,0 μg/mL.
Conclusiones
- La alta prevalencia de TVP en pacientes con COVID-19 está relacionada con resultados adversos.
- La profilaxis del tromboembolismo venoso puede ser beneficiosa para los pacientes de alto riesgo (puntuación de Padua ≥4).
- El COVID-19 puede ser un factor de riesgo independiente para la TVP en pacientes hospitalizados.
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