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Preparación para la pandemia: desarrollo de vacunas y anticuerpos terapéuticos para el COVID-19

Gregory D Sempowski¹, Kevin O Saunders², Priyamvada Acharya²

¹Department of Medicine, Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Pathology, Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.

|June 4, 2020

Resumen

La pandemia de COVID-19 requirió un rápido desarrollo de vacunas y terapias. Las asociaciones globales aprovecharon la investigación previa para la creación de contramedidas sin precedentes contra el SARS-CoV-2.

Área de la Ciencia:

* Virología e Inmunología
* Salud pública y epidemiología
* Biotecnología y Ciencias Farmacéuticas

Sus antecedentes:

* La pandemia del síndrome respiratorio agudo grave-coronavirus 2 (SARS-CoV-2), que causa el COVID-19, provocó importantes trastornos de salud y económicos en todo el mundo.
La necesidad urgente de intervenciones médicas eficaces impulsó esfuerzos mundiales sin precedentes.
* Los marcos existentes de brotes de enfermedades infecciosas anteriores informaron la respuesta.

Objetivo del estudio:

* Para destacar el rápido desarrollo de vacunas y contramedidas de anticuerpos contra el SARS-CoV-2.
* Para subrayar la naturaleza colaborativa de la respuesta global a la pandemia de COVID-19.
* Reconocer el papel fundamental de la investigación previa y las asociaciones.

Principales métodos:

* Revisión de las iniciativas mundiales de salud pública y publicaciones científicas relacionadas con las contramedidas contra el COVID-19.
* Análisis del papel de las colaboraciones entre el gobierno, la academia y el sector privado.
* Examen de la transferencia de tecnología y la adaptación de respuestas anteriores a enfermedades infecciosas emergentes.

Principales resultados:

* Velocidad sin precedentes en el desarrollo de vacunas y terapias de anticuerpos para COVID-19.
* Integración exitosa de diversos conocimientos especializados del sector público y privado.
* Eficacia demostrada de las plataformas de investigación establecidas para nuevas amenazas patógenas.

Conclusiones:

* La respuesta global al SARS-CoV-2 mostró el poder de la innovación colaborativa en las emergencias de salud pública.
* Las inversiones previas en infraestructuras de investigación y asociaciones intersectoriales fueron fundamentales para el rápido desarrollo de contramedidas.
* La respuesta a la pandemia proporciona un modelo para la preparación futura contra las enfermedades infecciosas emergentes.

Palabras clave:

▪▪▪ El tiempo

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