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Bases estructurales para bloquear la absorción de azúcar por el parásito de la malaria Plasmodium falciparum

Xin Jiang1, Yafei Yuan2, Jian Huang3

  • 1State Key Laboratory of Membrane Biology, Tsinghua University, Beijing 100084, China; Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China; School of Life Sciences, Tsinghua University, Beijing 100084, China.

Cell
|August 30, 2020
PubMed
Resumen

Los investigadores aclararon la estructura del parásito de la malaria

Palabras clave:
En el caso de losEn el caso de las bacterias de la especie Plasmodium falciparum:antipalúdicoestructura de cristaltransportador de glucosatransportador de hexosasBolsa inducida por el enlace con inhibidoresel parásito de la malariaDoble inhibición ortostérica y alostéricadescubrimiento de fármacos facilitado por la estructura

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