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El paisaje de la unión de ARN Pol II revela una transición gradual durante ZGA

Bofeng Liu1,2, Qianhua Xu1,2, Qiujun Wang1,2

  • 1Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, China.

Nature
|October 29, 2020
PubMed
Resumen

La activación del genoma cigótico (ZGA) implica la carga, la preconfiguración y la producción de ARN polimerasa II (Pol II). La ZGA menor es crucial para la preconfiguración de Pol II, asegurando el desarrollo embrionario adecuado y la activación génica.

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