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Updated: Dec 1, 2025

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
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Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

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Desaromatización nucleofílica de N-heteroaromáticos habilitada por los ácidos de Lewis y la catálisis del cobre

Xingchen Yan1, Luo Ge1, Marta Castiñeira Reis1

  • 1Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.

Journal of the American Chemical Society
|November 10, 2020
PubMed
Resumen

Este estudio introduce un nuevo sistema catalítico para la funcionalización aromática de las quinolinas, lo que permite una síntesis eficiente de compuestos heterocíclicos quirales. El método logra altos rendimientos y selectividades, superando los desafíos anteriores en las adiciones nucleófilas directas a los heteroaromáticos.

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