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Research and Development of High-performance Explosives
Published on: February 20, 2016
Examen de detección de deficiencia de vitamina D en adultos: Declaración de recomendación del grupo de trabajo de
, Alex H Krist1,2, Karina W Davidson3
1Fairfax Family Practice Residency, Fairfax, Virginia.
JAMA
|April 13, 2021
Resumen
No se recomienda la detección de deficiencia de vitamina D en adultos asintomáticos debido a la insuficiencia de pruebas. El Grupo de Trabajo de Servicios Preventivos de los Estados Unidos no encontró beneficios ni daños claros, lo que hace que el equilibrio sea incierto para esta población.
Área de la Ciencia:
- Endocrinología y Metabolismo
- La medicina preventiva
- Nutrición clínica
Sus antecedentes:
- La vitamina D es crucial para la homeostasis del calcio, el metabolismo óseo y varias funciones celulares.
- Los niveles óptimos de vitamina D y los puntos de corte de deficiencia carecen de consenso universal.
- Las necesidades individuales de vitamina D varían significativamente.
Objetivo del estudio:
- Revisar sistemáticamente las ventajas y los inconvenientes de la detección de la deficiencia de vitamina D.
- Actualizar las recomendaciones de 2014 del Grupo de Trabajo de Servicios Preventivos de los Estados Unidos (USPSTF).
- Evaluar la eficacia del cribado y del tratamiento precoz en adultos asintomáticos.
Principales métodos:
- Encargó una revisión sistemática de las pruebas existentes.
- Centrado en adultos no embarazados que viven en la comunidad y no tienen síntomas de deficiencia.
- Se incluyeron estudios sobre el cribado de beneficios y daños, y los resultados del tratamiento temprano.
Principales resultados:
- En general, no se encontraron pruebas de los beneficios del cribado de la deficiencia de vitamina D.
- No se pudo determinar el equilibrio entre los beneficios y los daños del cribado en adultos asintomáticos.
- El USPSTF emitió una "declaración I" indicando la insuficiencia de pruebas.
Conclusiones:
- La evidencia actual es insuficiente para evaluar los beneficios y los daños de la detección de deficiencia de vitamina D en adultos asintomáticos.
- El USPSTF no puede determinar el beneficio neto del cribado en esta población.
- Se necesita más investigación para aclarar el papel del cribado y el tratamiento precoz.
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