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Other Pulmonary Disorders01:17

Other Pulmonary Disorders

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Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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What is Cancer?02:12

What is Cancer?

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Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
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Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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Video Experimental Relacionado

Updated: Oct 28, 2025

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

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Cáncer de pulmón

Alesha A Thai1, Benjamin J Solomon1, Lecia V Sequist2

  • 1Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, VIC, Australia.

Lancet (London, England)
|July 17, 2021
PubMed
Resumen
Este resumen es generado por máquina.

El cáncer de pulmón sigue siendo una de las principales causas de muerte por cáncer en todo el mundo. Los avances recientes en las terapias dirigidas y los inhibidores del punto de control inmunológico han mejorado significativamente los resultados del tratamiento tanto para el cáncer de pulmón de células no pequeñas como para el de células pequeñas.

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Área de la Ciencia:

  • En el campo de la oncología
  • Pulmonología
  • Investigación del cáncer

Sus antecedentes:

  • El cáncer de pulmón es una de las principales preocupaciones de la salud mundial, causando millones de muertes al año.
  • En los últimos 20 años se han logrado avances significativos en la comprensión de la biología y el tratamiento del cáncer de pulmón.

Objetivo del estudio:

  • Proporcionar una visión global de los avances recientes en el tratamiento del cáncer de pulmón.
  • Para resaltar el progreso en las estrategias de detección, diagnóstico y tratamiento del cáncer de pulmón.

Principales métodos:

  • Revisión de la literatura actual y de los datos clínicos sobre el cáncer de pulmón.
  • Centrarse en las terapias dirigidas y los inhibidores del punto de control inmunológico.

Principales resultados:

  • Los avances en los biomarcadores predictivos han refinado la selección del tratamiento.
  • Las terapias dirigidas y los inhibidores del punto de control inmunológico han transformado los resultados de los pacientes.

Conclusiones:

  • La investigación continua y la aplicación de nuevas terapias son cruciales para mejorar la supervivencia del cáncer de pulmón.
  • Los enfoques de la medicina personalizada son clave para el manejo efectivo del cáncer de pulmón de células no pequeñas y de células pequeñas.