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ATP Driven Pumps II: P-type Pumps01:34

ATP Driven Pumps II: P-type Pumps

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The P-type pumps are a large family of integral membrane transporter ATPases. They are divided into five major types based on substrate specificity, from I to V.
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
5.4K
ATP Driven Pumps I: An Overview01:27

ATP Driven Pumps I: An Overview

9.1K
ATP-driven pumps, also known as transport ATPases, are integral membrane proteins. They have binding sites for ATP located on the membrane's cytosolic side and the ion-conducting domain in the transmembrane region. These pumps use the free energy released from ATP hydrolysis to move the solutes across cell membranes against an electrochemical gradient.
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
9.1K
ATP Driven Pumps III: V-type Pumps01:30

ATP Driven Pumps III: V-type Pumps

4.2K
V-type pumps are ATP-driven pumps found in the vacuolar membranes of plants, yeast, endosomal and lysosomal membranes of animal cells, plasma membranes of a few specialized eukaryotic cells, and some prokaryotes. They are also known as the V1Vo-ATPase, that couple ATP hydrolysis to transport protons against a concentration gradient.
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
4.2K
The Z-Scheme of Electron Transport in Photosynthesis01:34

The Z-Scheme of Electron Transport in Photosynthesis

11.3K
The light reactions of photosynthesis assume a linear flow of electrons from water to NADP+. During this process, light energy drives the splitting of water molecules to produce oxygen. However, oxidation of water molecules is a thermodynamically unfavorable reaction and requires a strong oxidizing agent. This is accomplished by the first product of light reactions: oxidized P680 (or P680+), the most powerful oxidizing agent known in biology. The oxidized P680 that acquires an electron from the...
11.3K
Photosystem I01:27

Photosystem I

67.5K
Although structurally similar to photosystem II (PSII), photosystem I (PSI) is has a different electron supplier and electron acceptor.
Both these photosystems work in concert. An excited electron from PSII is relayed to PSI via an electron transport chain in the thylakoid membrane of the chloroplast, which is comprised of the carrier molecule plastoquinone, the dual-protein cytochrome complex, and plastocyanin. As electrons move between PSII and PSI, they lose energy and must be re-energized...
67.5K
Chemiosmosis01:32

Chemiosmosis

106.3K
Oxidative phosphorylation is a highly efficient process that generates large amounts of adenosine triphosphate (ATP), the basic unit of energy that drives many cellular processes. Oxidative phosphorylation involves two processes— the electron transport chain and chemiosmosis.
Electron Transport Chain
The electron transport chain involves a series of protein complexes on the inner mitochondrial membrane that undergo a series of redox reactions. At the end of this chain, the electrons...
106.3K

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Video Experimental Relacionado

Updated: Oct 27, 2025

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging
08:40

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Published on: March 13, 2019

11.6K

Bomba supramolecular de segunda generación con combustible ligero

Martina Canton1,2, Jessica Groppi1,3, Lorenzo Casimiro1,4

  • 1CLAN-Center for Light Activated Nanostructures, ISOF-CNR, Via Gobetti 101, 40129 Bologna, Italy.

Journal of the American Chemical Society
|July 20, 2021
PubMed
Resumen
Este resumen es generado por máquina.

Este estudio presenta una nueva bomba supramolecular basada en pseudorotaxanos, que demuestra un funcionamiento autónomo impulsado por la luz en un estado de no equilibrio. El sistema diseñado permite la funcionalidad, lo que permite la integración en dispositivos avanzados.

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Área de la Ciencia:

  • Química supramolecular
  • Ciencias de los materiales
  • Ingeniería Química

Sus antecedentes:

  • Las bombas supramoleculares son esenciales para el transporte molecular controlado.
  • Los diseños anteriores carecían de modularidad y capacidades avanzadas de funcionalidad.
  • El funcionamiento autónomo en sistemas disipatorios es un desafío clave.

Objetivo del estudio:

  • Para presentar una bomba supramolecular modular basada en el pseudorotaxano.
  • Para demostrar su funcionamiento autónomo de no equilibrio impulsado fotoquímicamente.
  • Para permitir la funcionalidad para la integración en dispositivos complejos.

Principales métodos:

  • Diseño modular de los componentes del pseudorotaxano.
  • Ingeniería de paisajes energéticos a lo largo de las coordenadas de roscado.
  • Modulación de los perfiles de energía activada por la luz.
  • Caracterización de la operación autónoma de no equilibrio.

Principales resultados:

  • Diseño y síntesis exitosas de una bomba supramolecular modular.
  • Demostración del funcionamiento autónomo con accionamiento fotoquímico.
  • Se ha logrado un estado estacionario de no equilibrio en un régimen disipatorio.
  • Mínimos y máximos de energía de ingeniería para movimientos controlados.

Conclusiones:

  • La bomba supramolecular de segunda generación ofrece una mayor modularidad y funcionalidad.
  • El control fotoquímico permite el funcionamiento autónomo en sistemas disipadores.
  • Este sistema es un bloque de construcción prometedor para dispositivos supramoleculares avanzados.