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Updated: Oct 21, 2025

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Mecanismos alostéricos positivos de la analgesia mediada por el receptor de adenosina A

Christopher J Draper-Joyce1,2, Rebecca Bhola3, Jinan Wang4

  • 1Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.

Nature
|September 9, 2021
PubMed
Resumen

Este estudio introduce MIPS521, un nuevo modulador alostérico para el receptor de adenosina A1 (A1R), que demuestra un alivio eficaz del dolor no opioide en ratas. Destaca una nueva estrategia para desarrollar tratamientos específicos para el dolor neuropático.

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