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Veins of Head and Neck01:19

Veins of Head and Neck

3.4K
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
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Arteries of the Head and Neck01:26

Arteries of the Head and Neck

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The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
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Muscles that Move the Head01:19

Muscles that Move the Head

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The muscles that move the head are a dynamic and complex group of structures that work together to facilitate a wide range of head movements, including rotation, flexion, extension, and lateral bending.
The bilateral sternocleidomastoid, or SCM, and the suprahyoid and infrahyoid muscles are significant head flexors. The SCM muscles originate at the sternum and clavicle and attach to the mastoid process of the temporal bone. The SCM contracts bilaterally to bend the head forward, whereas...
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Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists01:28

Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists

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Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates...
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Video Experimental Relacionado

Updated: Oct 19, 2025

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
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Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Published on: April 20, 2018

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Cáncer de cabeza y cuello

Mayur D Mody1, James W Rocco2, Sue S Yom3

  • 1Department of Hematology and Medical Oncology, The Winship Cancer Institute, Emory University, Atlanta, GA, USA.

Lancet (London, England)
|September 25, 2021
PubMed
Resumen

Los cánceres de cabeza y cuello, a menudo carcinoma de células escamosas, son un desafío mundial. El tratamiento requiere un enfoque multidisciplinario adaptado a sitios e histologías específicos, con investigaciones en curso centradas en mejorar los resultados de los pacientes.

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Área de la Ciencia:

  • En el campo de la oncología
  • Otorrinolaringología

Sus antecedentes:

  • El cáncer de cabeza y cuello es el séptimo cáncer maligno más común a nivel mundial, que afecta al tracto aerodigestivo superior.
  • El carcinoma de células escamosas es la histología predominante, con el tabaco, el alcohol y los virus (HPV, EBV) como factores de riesgo clave.
  • Estas neoplasias presentan desafíos complejos de tratamiento, que requieren una estrategia multidisciplinaria.

Objetivo del estudio:

  • Proporcionar una visión global de la comprensión actual del cáncer de cabeza y cuello.
  • Centrarse en los principios establecidos para el tratamiento de estos tumores malignos.
  • Para discutir las direcciones emergentes para mejorar los resultados de los pacientes.

Principales métodos:

  • Revisión de la literatura actual y comprensión clínica del cáncer de cabeza y cuello.
  • Análisis de las modalidades de tratamiento establecidas, incluyendo cirugía, radioterapia y terapia sistémica.
  • Exploración de las variaciones del tratamiento específicas del sitio y de la histología.

Principales resultados:

  • Los cánceres de cabeza y cuello son diversos, siendo el carcinoma de células escamosas el más común.
  • Los factores de riesgo están bien definidos, incluidas las opciones de estilo de vida y las infecciones virales.
  • El tratamiento multidisciplinario es esencial para la enfermedad localmente avanzada.

Conclusiones:

  • Las estrategias de tratamiento deben ser individualizadas en función del sitio del cáncer y la histología.
  • La investigación continua y la exploración de nuevos enfoques terapéuticos son cruciales.
  • Mejorar los resultados de los pacientes sigue siendo un objetivo primordial en el manejo de los tumores malignos de cabeza y cuello.