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Updated: Oct 17, 2025

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
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Nucleoside Triphosphates - From Synthesis to Biochemical Characterization

Published on: April 3, 2014

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Síntesis y reconocimiento por polimerasa de los trifosfatos de ácido nucleico treosa dotados de diversas

Qingfeng Li, Victoria A Maola, Nicholas Chim

    Journal of the American Chemical Society
    |October 12, 2021
    PubMed
    Resumen

    Los investigadores sintetizaron nuevos polímeros genéticos no naturales (XNA) con diversos grupos funcionales para mejorar la estabilidad terapéutica del aptamer y la afinidad de unión. Una polimerasa desarrollada en el laboratorio reconoció estos nucleósidos trifosfatados modificados, expandiendo las capacidades de la biología sintética.

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