Jove
Visualize
Contáctanos

Videos de Conceptos Relacionados

The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

2.9K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.9K
Aging01:26

Aging

316
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
316
Mitochondria01:37

Mitochondria

15.6K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
15.6K
Cancer Prevention02:59

Cancer Prevention

6.4K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
6.4K
Lifestyle Factors and Health01:20

Lifestyle Factors and Health

220
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
220
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

63
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
63

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Dietary Protein Restriction Ameliorates Cardiac Inflammaging via AMPK-ULK1-Mediated Mitochondrial Quality Control.

Aging cell·2026
Same author

Low protein-induced-FGF-21 signaling remodels adipose tissue on reduced markers of senescence during aging.

GeroScience·2025
Same author

The companion dog as a translational model for Alzheimer's disease: Development of a longitudinal research platform and post mortem protocols.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Health octo tool matches personalized health with rate of aging.

Nature communications·2025
Same author

Mapping mitochondrial aging.

eLife·2024
Same author

Mitochondrial transplants to treat mitochondrial dysfunction.

Nature metabolism·2024
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Video Experimental Relacionado

Updated: Oct 13, 2025

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
11:44

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B

Published on: January 19, 2022

2.7K

Las dietas antienvejecimiento: Separando los hechos de la ficción

Mitchell B Lee1, Cristal M Hill2, Alessandro Bitto1

  • 1Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195-7470, USA.

Science (New York, N.Y.)
|November 18, 2021
PubMed
Resumen

La restricción calórica y varias intervenciones dietéticas son prometedoras para prolongar la vida y retrasar el envejecimiento. La investigación explora sus mecanismos superpuestos y las vías de envejecimiento conservadas.

Más Videos Relacionados

A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae
10:39

A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae

Published on: September 17, 2020

6.5K
Solid Plate-based Dietary Restriction in Caenorhabditis elegans
06:13

Solid Plate-based Dietary Restriction in Caenorhabditis elegans

Published on: May 28, 2011

16.8K

Videos de Experimentos Relacionados

Last Updated: Oct 13, 2025

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
11:44

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B

Published on: January 19, 2022

2.7K
A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae
10:39

A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae

Published on: September 17, 2020

6.5K
Solid Plate-based Dietary Restriction in Caenorhabditis elegans
06:13

Solid Plate-based Dietary Restriction in Caenorhabditis elegans

Published on: May 28, 2011

16.8K

Área de la Ciencia:

  • Gerontología y ciencias nutricionales.
  • Centrarse en los mecanismos de envejecimiento y la prolongación de la vida.

Sus antecedentes:

  • La restricción calórica (CR) es un método bien establecido para extender la vida útil y retrasar las enfermedades relacionadas con la edad en modelos animales.
  • Las estrategias dietéticas emergentes como el ayuno intermitente y las dietas cetogénicas ofrecen nuevas perspectivas sobre los procesos de envejecimiento.

Objetivo del estudio:

  • Revisar las modalidades alternativas de dieta antienvejecimiento más allá de la restricción calórica.
  • Explorar las perspectivas mecanicistas y las posibles aplicaciones clínicas de estas dietas.
  • Evaluar los mecanismos biológicos conservados que subyacen al envejecimiento.

Principales métodos:

  • Revisión de la literatura de los estudios sobre las diversas intervenciones dietéticas.
  • Análisis de las percepciones mecanicistas del ayuno intermitente, las dietas cetogénicas, la restricción de proteínas, etc.
  • Comparación de la eficacia y los mecanismos de superposición entre las diferentes estrategias dietéticas.

Principales resultados:

  • Múltiples intervenciones dietéticas, incluido el ayuno intermitente y las dietas cetogénicas, muestran un potencial de efectos antienvejecimiento.
  • Estas dietas parecen actuar a través de vías biológicas parcialmente superpuestas y conservadas.
  • La eficacia de estas dietas populares fuera de los entornos de laboratorio requiere más investigación.

Conclusiones:

  • Las intervenciones dietéticas ofrecen vías prometedoras para modular los procesos de envejecimiento.
  • La comprensión de los mecanismos de envejecimiento conservados es clave para desarrollar estrategias eficaces contra el envejecimiento.
  • Se necesita más investigación para validar las aplicaciones clínicas de estas dietas en humanos.