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Updated: Oct 4, 2025

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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Published on: November 30, 2022

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Semi-síntesis de (-) - bufospirostenina A habilitada por la reacción de reordenamiento de la fotosantonina

Jun Huang1, Tingting Cao1, Zhongchao Zhang1

  • 1State Key Laboratory of Chemical Oncogenomics and Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.

Journal of the American Chemical Society
|February 3, 2022
PubMed
Resumen

Este estudio detalla una semisíntesis enantioselectiva de la (-) -bufospirostenina A. Los pasos clave incluyen un reordenamiento biomimético para el núcleo cíclico y la isomerización catalizada por cobalto para la instalación de enlaces dobles.

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