Video Experimental Relacionado

Updated: May 11, 2026

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
11:02

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 18, 2013

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Caracterización genómica de los patrones metastásicos de la secuenciación clínica prospectiva de 25.000 pacientes

Bastien Nguyen1, Christopher Fong1, Anisha Luthra1

  • 1Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Cell
|February 5, 2022
PubMed
Resumen

Las alteraciones genómicas impulsan la metástasis del cáncer, la principal causa de muerte por cáncer. Este estudio analizó a 25.000 pacientes con cáncer metastásico, revelando vínculos entre cambios genómicos, inestabilidad cromosómica y propagación metastásica en 50 tipos de tumor.

Palabras clave:
Secuenciación del ADNel cáncersecuenciación clínicaLa genómicaLas metástasisPerfiles molecularesmutacionessecuenciación de próxima generaciónEl organtropismocáncer de páncreas

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