Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...
Maxwell's Equation Of Electromagnetism01:29

Maxwell's Equation Of Electromagnetism

James Clerk Maxwell (1831–1879) was one of the major contributors to physics in the nineteenth century. Although he died young, he made major contributions to the development of the kinetic theory of gases, to the understanding of color vision, and to understanding the nature of Saturn's rings. He is probably best known for having combined existing knowledge on the laws of electricity and magnetism with his insights into a complete overarching electromagnetic theory, which is represented by...
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Noncompartmental Analysis: Statistical Moment Theory00:56

Noncompartmental Analysis: Statistical Moment Theory

Noncompartmental analyses leverage statistical moment theory to examine time-related changes in macroscopic events, encapsulating the collective outcomes stemming from the constituent elements in play. Statistical moment theory is a mathematical approach used to describe the time course of drug concentration in the body without assuming a specific compartmental model. SMT provides insights into drug absorption, distribution, metabolism, and elimination by treating drug concentration versus time...
Noncompartmental Analysis: Mean Residence Time01:05

Noncompartmental Analysis: Mean Residence Time

According to statistical moment theory, mean residence time (MRT) is an important measure in pharmacokinetics. MRT can be defined as the expected mean of a probability density function distribution. It provides valuable insights into drug disposition in the body.
After the administration of a drug through intravenous bolus injection, the drug molecules are distributed throughout the body and remain there for varying periods. The MRT represents the average time these drug molecules stay in the...
Holter Monitor: 24-Hour Monitoring01:23

Holter Monitor: 24-Hour Monitoring

Holter monitoring is a continuous electrocardiography (ECG) recording that tracks the heart's electrical activity over an extended period, generally 24 to 48 hours. This noninvasive diagnostic tool detects irregular heart rhythms that may not be captured during a standard ECG performed in a clinical setting.DeviceThe Holter monitor is a portable, small device connected to several electrodes on the patient's chest. These electrodes detect the heart's electrical signals and transmit them to the...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

[Pierre Tiollais (1934-2024), a pioneer in genetic engineering with a lifelong commitment to the hepatitis B virus].

Medecine sciences : M/S·2025
Same author

Biographical Feature: In memoriam Pierre Tiollais (1934-2024).

Journal of virology·2025
Same author

Biographical Feature: In memoriam Pierre Tiollais (1934-2024).

Journal of virology·2025
Same author

Biographical Feature: In memoriam Pierre Tiollais (1934-2024).

Journal of virology·2025
Same author

Biographical Feature: In memoriam Pierre Tiollais (1934-2024).

Journal of virology·2025
Same author

Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.

Structure (London, England : 1993)·2022
Same journal

A native sulfur deposit in Gale crater, Mars.

Science (New York, N.Y.)·2026
Same journal

Coordinated demise of harmful algal blooms.

Science (New York, N.Y.)·2026
Same journal

Genetic effects put into context.

Science (New York, N.Y.)·2026
Same journal

Bacteria share proteins to survive antibiotics.

Science (New York, N.Y.)·2026
Same journal

Impacts shaped Earth's first continents.

Science (New York, N.Y.)·2026
Same journal

Erratum for the Report "Covalently bonded single-molecule junctions with stable and reversible photoswitched conductivity" by C. Jia <i>et al</i>.

Science (New York, N.Y.)·2026
Ver todos los artículos relacionados

Video Experimental Relacionado

Updated: Jun 6, 2026

Two-photon Imaging of Microglial Processes' Attraction Toward ATP or Serotonin in Acute Brain Slices
07:27

Two-photon Imaging of Microglial Processes' Attraction Toward ATP or Serotonin in Acute Brain Slices

Published on: January 31, 2019

10.5K

Luc Montagnier (1932-2022) fue un actor francés.

Robin A Weiss1, Simon Wain-Hobson2

  • 1Division of Infection and Immunity, University College London, London, UK.

Science (New York, N.Y.)
|March 17, 2022
PubMed
Resumen
Este resumen es generado por máquina.

Luc Montagnier descubrió el virus de la inmunodeficiencia humana (VIH), la causa del SIDA. Su trabajo innovador identificó el retrovirus responsable de la crisis de salud mundial.

Más Videos Relacionados

Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases
09:36

Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases

Published on: June 28, 2019

10.8K
Profiling Ubiquitin and Ubiquitin-like Dependent Post-translational Modifications and Identification of Significant Alterations
10:26

Profiling Ubiquitin and Ubiquitin-like Dependent Post-translational Modifications and Identification of Significant Alterations

Published on: November 7, 2019

6.2K

Videos de Experimentos Relacionados

Last Updated: Jun 6, 2026

Two-photon Imaging of Microglial Processes' Attraction Toward ATP or Serotonin in Acute Brain Slices
07:27

Two-photon Imaging of Microglial Processes' Attraction Toward ATP or Serotonin in Acute Brain Slices

Published on: January 31, 2019

10.5K
Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases
09:36

Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases

Published on: June 28, 2019

10.8K
Profiling Ubiquitin and Ubiquitin-like Dependent Post-translational Modifications and Identification of Significant Alterations
10:26

Profiling Ubiquitin and Ubiquitin-like Dependent Post-translational Modifications and Identification of Significant Alterations

Published on: November 7, 2019

6.2K

Área de la Ciencia:

  • Virología
  • Inmunología
  • Enfermedades infecciosas

Sus antecedentes:

  • El surgimiento del Síndrome de Inmunodeficiencia Adquirida (SIDA) presentó un importante desafío para la salud mundial.
  • Identificar el agente causante era crucial para comprender, diagnosticar y tratar la enfermedad.

Objetivo del estudio:

  • Para aislar e identificar el virus responsable del SIDA.
  • Para caracterizar el agente etiológico de la nueva epidemia.

Principales métodos:

  • Aislamiento de linfocitos de pacientes con síndrome de linfadenopatía.
  • Cultivo de estas células mediante técnicas específicas para detectar la actividad de la transcriptasa inversa.
  • Microscopía electrónica para visualizar las partículas virales.

Principales resultados:

  • Aislamiento y cultivo exitosos de un nuevo retrovirus de muestras de pacientes.
  • Identificación del retrovirus como el agente causante del SIDA.
  • Caracterización de la estructura y el ciclo de replicación del virus.

Conclusiones:

  • El virus de la inmunodeficiencia humana (VIH) fue identificado como el agente etiológico del SIDA.
  • Este descubrimiento allanó el camino para las pruebas de diagnóstico y estrategias terapéuticas.
  • El trabajo de Montagnier avanzó fundamentalmente en la comprensión de la retrovirología y las enfermedades infecciosas.