Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Catalysis02:50

Catalysis

27.7K
The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.
27.7K
Coupled Reactions01:17

Coupled Reactions

8.6K
Cellular processes such as building and breaking down complex molecules occur through stepwise chemical reactions. Some of these chemical reactions are spontaneous and release energy, whereas others require energy to proceed. Cells often couple the energy-releasing reaction with the energy-requiring one to carry out important cell functions. 
Energy in adenosine triphosphate or ATP molecules is easily accessible to do work. ATP powers the majority of energy-requiring cellular reactions....
8.6K
Introduction to Mechanisms of Enzyme Catalysis01:13

Introduction to Mechanisms of Enzyme Catalysis

9.0K
For many years, scientists thought that enzyme-substrate binding took place in a simple "lock-and-key" fashion. This model stated that the enzyme and substrate fit together perfectly in one instantaneous step. However, current research supports a more refined view scientists call induced fit. The induced-fit model expands upon the lock-and-key model by describing a more dynamic interaction between enzyme and substrate. As the enzyme and substrate come together, their interaction causes...
9.0K
Factors Affecting Activity Coefficient01:17

Factors Affecting Activity Coefficient

1.0K
The extended Debye-Hückel equation indicates that the activity coefficient of an ion in an aqueous solution at 25°C depends on three partially interdependent properties: the ionic strength of the solution, the charge of the ion, and the ion size. 
The activity coefficient value for an ion is close to one when the solution has almost zero ionic strength, i.e., when the solution shows close to ideal behavior. As the ionic strength of the solution increases from 0 to 0.1 mol/L, a...
1.0K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

2.6K
2.6K
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

5.0K
Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
5.0K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Binding of Aqueous-Stable, Lipophilic, Hemocompatible Anticancer V<sup>V</sup>O<sub>2</sub> Metallodrugs with Biological Molecules: X-ray Structures of the Adduct of the V<sup>V</sup>-hydrazonato Complex with Hen Egg White Lysozyme.

Inorganic chemistry·2026
Same author

Dual Metal Complex Functionalization of Black Phosphorus.

Nano letters·2026
Same author

Macrocyclic Ruthenium Ring Expansion Metathesis Polymerization Initiators Exhibit Tether Length-Dependent Behavior.

Organometallics·2025
Same author

Molecular Plasmonic Cavities.

Nano letters·2025
Same author

Synthesis of Oxasilolanes by TBAT-Catalyzed Hydroxyl-Directed Hydrosilylation.

The Journal of organic chemistry·2025
Same author

Solid-State Packing Controls Exciton Delocalization and Photophysics in Nonfullerene Acceptors.

Journal of the American Chemical Society·2025

Video Experimental Relacionado

Updated: Sep 22, 2025

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions
10:22

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions

Published on: June 16, 2014

18.3K

Dinámica del sitio multiactivo en un catalizador de racimo molecular Cr/Co/Se

Jonathan A Kephart1, Benjamin S Mitchell1, Werner Kaminsky1

  • 1Department of Chemistry, University of Washington, Seattle, Washington 98195, United States.

Journal of the American Chemical Society
|May 20, 2022
PubMed
Resumen

Esta investigación revela cómo tres sitios activos en un nanocluster trabajan juntos para las reacciones químicas. Comprender esta reactividad interconectada es clave para desarrollar nuevos catalizadores para la formación de carbodiimida.

Más Videos Relacionados

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
08:25

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs

Published on: January 17, 2020

7.4K
Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics
10:52

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Published on: April 12, 2019

13.0K

Videos de Experimentos Relacionados

Last Updated: Sep 22, 2025

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions
10:22

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions

Published on: June 16, 2014

18.3K
Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
08:25

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs

Published on: January 17, 2020

7.4K
Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics
10:52

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Published on: April 12, 2019

13.0K

Área de la Ciencia:

  • Química inorgánica
  • Ciencia de los nanomateriales
  • Catálisis

Sus antecedentes:

  • Los nanocúmulos atómicamente precisos ofrecen propiedades catalíticas únicas debido a sus estructuras definidas.
  • Comprender la interacción entre múltiples sitios activos es crucial para el diseño de catalizadores eficientes.

Objetivo del estudio:

  • Investigar la reactividad interconectada de los tres sitios activos en el nanocúmulo Cr3(py) 3Co6Se8L6 (1(py) 3.
  • Para aclarar el mecanismo de activación de azido de tosilo y la formación de carbodiimida catalizada por este nanocluster.

Principales métodos:

  • Se utilizaron estudios catalíticos y estequiométricos para examinar la activación del azido tosílico.
  • Se realizaron el aislamiento y la caracterización cristalográfica de los principales intermedios metal-imido.
  • Se utilizaron análisis estructurales comparativos y estudios de unión al sustrato.

Principales resultados:

  • Se aislaron y caracterizaron los principales intermediarios catalíticamente competentes, incluidos los grupos tris (imido) y mono (imido).
  • La transferencia de nitreno se produce mediante un mecanismo escalonado que implica la activación secuencial de los tres sitios activos.
  • El estado químico de los sitios vecinos influye en la afinidad del sustrato en los sitios individuales de Cr-imido.

Conclusiones:

  • El estudio demuestra la reactividad interconectada de múltiples sitios activos en un catalizador de nanoagrupación.
  • Se logró una comprensión mecánica detallada de la formación de carbodiimida.
  • Los hallazgos proporcionan información sobre la regulación de la unión al sustrato por sitios activos vecinos en la catálisis de nanoagrupaciones.