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Síntesis de un compuesto de cloruro de manganeso estable en el banco: química de coordinación y diclorinación de
Ananya Saju, Justin R Griffiths, Samantha N MacMillan1
1Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Journal of the American Chemical Society
|September 6, 2022
Resumen
Un nuevo complejo de cloruro de manganeso, [MnCl3(OPPh3) 2], proporciona una fuente estable y accesible de tricloruro de manganeso (MnCl3). Este complejo facilita varias aplicaciones sintéticas, incluidas las diclorinaciones de alquenos y las reacciones de coordinación, a través de un mecanismo radical.
Área de la Ciencia:
- Química inorgánica
- Química organometálica
- Química sintética
Sus antecedentes:
- El tricloruro de manganeso (MnCl3) es una especie reactiva a menudo difícil de manejar y preparar.
- Los métodos sintéticos existentes que requieren soluciones de MnCl3 son a menudo engorrosos y limitados.
- Se necesitan fuentes de MnCl3 estables y de fácil acceso para diversas transformaciones químicas.
Objetivo del estudio:
- Para sintetizar y caracterizar un complejo de cloruro de manganeso estable, [MnCl3(OPPh3) ] (1), como una fuente conveniente de MnCl3.
- Demostrar la utilidad del complejo 1 en química de coordinación y metodologías sintéticas.
- Para elucidar el mecanismo de reacción, en particular en las reacciones de dicloración de alquenos.
Principales métodos:
- Síntesis de [MnCl3 ((OPPh3) 2) ] (1) mediante la reacción del MnCl3 solvado con acetonitrilo (2) con el óxido de trifenilfosfina (Ph3PO).
- Utilizando el complejo 1 para las reacciones de coordinación, ejemplificado por la síntesis de {Tpm*} MnCl3 (3).
- Realización de reacciones de dicloración de alquenos utilizando el complejo 1 en varios disolventes en condiciones aeróbicas.
- Investigación de los mecanismos de reacción mediante halogenación acelerada por la luz y experimentos sensibles a los radicales.
Principales resultados:
- El complejo 1 se preparó con éxito como un precipitado azul estable en banco.
- El complejo 1 sirvió efectivamente como precursor para sintetizar {Tpm*}MnCl3 (3).
- Las diclorinaciones de alqueno se lograron con un buen alcance del sustrato utilizando el complejo 1 en diversos disolventes, abiertos al aire.
- La evidencia sugiere un mecanismo radical que involucra la transferencia gradual de átomos de cloro desde el complejo 1.
Conclusiones:
- El complejo [MnCl3 ((OPPh3) 2) ] (1) es un reactivo valioso y práctico, que ofrece una alternativa estable y fácil de manejar a las soluciones tradicionales de MnCl3.
- El complejo 1 amplía el alcance de las aplicaciones sintéticas que involucran al MnCl3, lo que permite una dicloración eficiente de los alquenos y facilita la química de coordinación.
- La reactividad observada apoya una vía radical para las transformaciones mediadas por el complejo 1, avanzando la comprensión mecanicista en la química del manganeso.
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