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Updated: Aug 29, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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Ciclopropano-Fusionado N-Heterociclos a través de Aza-Heck-Triggered C ((sp3) -H Cascadas de funcionalidad

Changcheng Jing1, Benjamin T Jones2, Ross J Adams1

  • 1Department of Chemistry, University of Liverpool, Crown Street, Liverpool L69 7ZD, United Kingdom.

Journal of the American Chemical Society
|September 9, 2022
PubMed
Resumen

Este estudio introduce nuevas reacciones de aza-Heck para la funcionalización de C ((sp3)-H, creando ciclopropanos a través de la catálisis del paladio. La investigación detalla los factores que controlan la selectividad del sitio para diversos sistemas fusionados.

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